Evaluation of antiretroviral regimen switching options in adults with HIV with sustained viral load non-suppression on dolutegravir, lamivudine, and tenofovir in eastern, central, southern, and western Africa: a modelling study.

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Title: Evaluation of antiretroviral regimen switching options in adults with HIV with sustained viral load non-suppression on dolutegravir, lamivudine, and tenofovir in eastern, central, southern, and western Africa: a modelling study.
Authors: Phillips AN; Institute for Global Health, UCL, London, UK. Electronic address: andrew.phillips@ucl.ac.uk., Bansi-Matharu L; Institute for Global Health, UCL, London, UK., van Oosterhout JJ; Partners in Hope, Lilongwe, Malawi; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Hyle E; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., van de Vijver D; Erasmus Medical Centre, Erasmus University, Rotterdam, Netherlands., Kouyos R; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Hong SY; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA., Chun H; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA., Raizes E; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kantor R; Department of Medicine, Brown University Warren Alpert Medical School, Providence, RI, USA., Jordan MR; Department of Medicine and Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA; Global Health and Tropical Medicine, LA-REAL, Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa, Lisbon, Portugal., Vitoria M; Department of Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland., Ford N; Department of Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland; Centre for Integrated Data and Epidemiological Research, University of Cape Town, Cape Town, South Africa., Mugurungi O; Ministry of Health and Child Care, Harare, Zimbabwe., Apollo T; Ministry of Health and Child Care, Harare, Zimbabwe., Chimberengwa P; Department of Community Medicine, National University of Science and Technology, Bulawayo, Zimbabwe., Meintjes G; Department of Medicine, University of Cape Town, Cape Town, South Africa; Blizard Institute, Queen Mary University of London, London, UK., Siedner M; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Lundgren J; Centre of Excellence for Health, Immunity, and Infections, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Schapiro J; National Hemophilia Center, Sheba Medical Center, Ramat Gan, Israel., Flexner C; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Loosli T; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Institute of Medical Virology, University of Zurich, Zurich, Switzerland., Cambiano V; Institute for Global Health, UCL, London, UK., Smith J; Institute for Global Health, UCL, London, UK., Xia R; Institute for Global Health, UCL, London, UK., McCluskey S; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Mewoabi S; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon., Calmy A; Geneva University Hospitals, Geneva, Switzerland., Eholie SP; Unit of Infectious and Tropical Diseases, Treichville University Teaching Hospital, Abidjan, Côte d'Ivoire., Revill P; Centre for Health Economics, University of York, York, UK.
Source: The lancet. HIV [Lancet HIV] 2025 Aug; Vol. 12 (8), pp. e578-e586. Date of Electronic Publication: 2025 Jun 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101645355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3018 (Electronic) Linking ISSN: 23523018 NLM ISO Abbreviation: Lancet HIV Subsets: MEDLINE
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  Data: Evaluation of antiretroviral regimen switching options in adults with HIV with sustained viral load non-suppression on dolutegravir, lamivudine, and tenofovir in eastern, central, southern, and western Africa: a modelling study.
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  Data: <searchLink fieldCode="AU" term="%22Phillips+AN%22">Phillips AN</searchLink>; Institute for Global Health, UCL, London, UK. Electronic address: andrew.phillips@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Bansi-Matharu+L%22">Bansi-Matharu L</searchLink>; Institute for Global Health, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Oosterhout+JJ%22">van Oosterhout JJ</searchLink>; Partners in Hope, Lilongwe, Malawi; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hyle+E%22">Hyle E</searchLink>; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22van+de+Vijver+D%22">van de Vijver D</searchLink>; Erasmus Medical Centre, Erasmus University, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kouyos+R%22">Kouyos R</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hong+SY%22">Hong SY</searchLink>; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Chun+H%22">Chun H</searchLink>; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Raizes+E%22">Raizes E</searchLink>; Division of Global HIV and TB, Global Health Center, Centers for Disease Control and Prevention, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kantor+R%22">Kantor R</searchLink>; Department of Medicine, Brown University Warren Alpert Medical School, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Jordan+MR%22">Jordan MR</searchLink>; Department of Medicine and Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA; Global Health and Tropical Medicine, LA-REAL, Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Vitoria+M%22">Vitoria M</searchLink>; Department of Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ford+N%22">Ford N</searchLink>; Department of Global HIV, Hepatitis, and Sexually Transmitted Infections Programmes, World Health Organization, Geneva, Switzerland; Centre for Integrated Data and Epidemiological Research, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Mugurungi+O%22">Mugurungi O</searchLink>; Ministry of Health and Child Care, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Apollo+T%22">Apollo T</searchLink>; Ministry of Health and Child Care, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Chimberengwa+P%22">Chimberengwa P</searchLink>; Department of Community Medicine, National University of Science and Technology, Bulawayo, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Meintjes+G%22">Meintjes G</searchLink>; Department of Medicine, University of Cape Town, Cape Town, South Africa; Blizard Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Siedner+M%22">Siedner M</searchLink>; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lundgren+J%22">Lundgren J</searchLink>; Centre of Excellence for Health, Immunity, and Infections, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Schapiro+J%22">Schapiro J</searchLink>; National Hemophilia Center, Sheba Medical Center, Ramat Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Flexner+C%22">Flexner C</searchLink>; Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Loosli+T%22">Loosli T</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cambiano+V%22">Cambiano V</searchLink>; Institute for Global Health, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Smith+J%22">Smith J</searchLink>; Institute for Global Health, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Xia+R%22">Xia R</searchLink>; Institute for Global Health, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22McCluskey+S%22">McCluskey S</searchLink>; Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mewoabi+S%22">Mewoabi S</searchLink>; Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.<br /><searchLink fieldCode="AU" term="%22Calmy+A%22">Calmy A</searchLink>; Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Eholie+SP%22">Eholie SP</searchLink>; Unit of Infectious and Tropical Diseases, Treichville University Teaching Hospital, Abidjan, Côte d'Ivoire.<br /><searchLink fieldCode="AU" term="%22Revill+P%22">Revill P</searchLink>; Centre for Health Economics, University of York, York, UK.
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