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Advanced tissue-engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.

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Title: Advanced tissue-engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.
Authors: Luo H; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Anderson CW; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Department of Bioengineering, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States., Li X; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Lu Y; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06510, United States., Hoareau M; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Xing Q; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States., Fooladi S; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States., Liu Y; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Pathology, Yale University, New Haven, CT 06520, United States., Xu Z; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Park J; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Physiology, College of Medicine, Hallym University, Hallymdaehak-gil, Chuncheon-si, Gangwon-Do 24252, South Korea., Fallon ME; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Thomas J; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States., Gruber PJ; Department of Pathology, Yale University, New Haven, CT 06520, United States; Department of Surgery, Yale University, New Haven, CT 06520, United States., Elder RW; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Department of Pediatrics, Yale School of Medicine, New Haven, CT 06520, United States., Mak M; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States; Department of Pharmacological Sciences, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, United States., Riaz M; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States., Campbell SG; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States., Qyang Y; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States; Department of Pathology, Yale University, New Haven, CT 06520, United States. Electronic address: yibing.qyang@yale.edu.
Source: Acta biomaterialia [Acta Biomater] 2026 Feb; Vol. 211, pp. 92-103. Date of Electronic Publication: 2025 Jun 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE; In Process
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  Data: Advanced tissue-engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.
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  Data: <searchLink fieldCode="AU" term="%22Luo+H%22">Luo H</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Anderson+CW%22">Anderson CW</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Department of Bioengineering, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Hoareau+M%22">Hoareau M</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Xing+Q%22">Xing Q</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Fooladi+S%22">Fooladi S</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Pathology, Yale University, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Xu+Z%22">Xu Z</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Physiology, College of Medicine, Hallym University, Hallymdaehak-gil, Chuncheon-si, Gangwon-Do 24252, South Korea.<br /><searchLink fieldCode="AU" term="%22Fallon+ME%22">Fallon ME</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Thomas+J%22">Thomas J</searchLink>; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Gruber+PJ%22">Gruber PJ</searchLink>; Department of Pathology, Yale University, New Haven, CT 06520, United States; Department of Surgery, Yale University, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Elder+RW%22">Elder RW</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Department of Pediatrics, Yale School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Mak+M%22">Mak M</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States; Department of Pharmacological Sciences, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, United States.<br /><searchLink fieldCode="AU" term="%22Riaz+M%22">Riaz M</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States.<br /><searchLink fieldCode="AU" term="%22Campbell+SG%22">Campbell SG</searchLink>; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States.<br /><searchLink fieldCode="AU" term="%22Qyang+Y%22">Qyang Y</searchLink>; Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine, New Haven, CT 06511, United States; Yale Stem Cell Center, New Haven, CT 06520, United States; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, United States; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, United States; Department of Pathology, Yale University, New Haven, CT 06520, United States. Electronic address: yibing.qyang@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%22101233144%22">Acta biomaterialia</searchLink> [Acta Biomater] 2026 Feb; Vol. 211, pp. 92-103. <i>Date of Electronic Publication: </i>2025 Jun 27.
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