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Randomised controlled trials for improving health outcomes for people living with multiple long-term conditions: Protocol for a systematic review of methodological approaches, risk of bias and reporting quality.

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Title: Randomised controlled trials for improving health outcomes for people living with multiple long-term conditions: Protocol for a systematic review of methodological approaches, risk of bias and reporting quality.
Authors: Zhang L; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Fisher E; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom., Bradbury N; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Darko N; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Khunti K; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.; Diabetes Research Centre, University of Leicester, Leicester, United Kingdom., Lock S; Library and Learning Services, University of Leicester, Leicester, United Kingdom., Singh SJ; Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom., Simpson SA; Medical Research Council and Scottish Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom., Smith E; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom., Smith SM; Discipline of Public Health and Primary Care, Trinity College, Dublin, Ireland., Taylor RS; Medical Research Council and Scottish Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.; Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom., Witham M; Newcastle Biomedical Research Centre, Newcastle University, Newcastle, United Kingdom., Young H; University Hospitals of Leicester, Leicester, United Kingdom., Gray LJ; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.
Source: PloS one [PLoS One] 2025 Jun 30; Vol. 20 (6), pp. e0325742. Date of Electronic Publication: 2025 Jun 30 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Randomised controlled trials for improving health outcomes for people living with multiple long-term conditions: Protocol for a systematic review of methodological approaches, risk of bias and reporting quality.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fisher+E%22">Fisher E</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bradbury+N%22">Bradbury N</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Darko+N%22">Darko N</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Khunti+K%22">Khunti K</searchLink>; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.; Diabetes Research Centre, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lock+S%22">Lock S</searchLink>; Library and Learning Services, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Singh+SJ%22">Singh SJ</searchLink>; Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Simpson+SA%22">Simpson SA</searchLink>; Medical Research Council and Scottish Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Smith+E%22">Smith E</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Smith+SM%22">Smith SM</searchLink>; Discipline of Public Health and Primary Care, Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Taylor+RS%22">Taylor RS</searchLink>; Medical Research Council and Scottish Chief Scientist Office, Social and Public Health Sciences Unit, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.; Robertson Centre for Biostatistics, School of Health and Well Being, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Witham+M%22">Witham M</searchLink>; Newcastle Biomedical Research Centre, Newcastle University, Newcastle, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Young+H%22">Young H</searchLink>; University Hospitals of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gray+LJ%22">Gray LJ</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Jun 30; Vol. 20 (6), pp. e0325742. <i>Date of Electronic Publication: </i>2025 Jun 30 (<i>Print Publication: </i>2025).
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