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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.

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Title: A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
Authors: Park SJ; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Research Institute for Korean Medicine, Pusan National University, Yangsan-si, South Korea., Lukkes JL; Department of Psychiatry., Chan KK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Drozd HP; Medical Scientist Training Program., Burgin CB; Department of Dermatology, and., Qian S; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Sullivan MM; Department of Psychiatry., Guevara CG; Department of Psychiatry., Cunningham N; Department of Psychiatry., Arenas S; Department of Psychiatry., Collins MA; Department of Psychiatry., Zucker J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Won J; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Smith A; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Jiang L; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Mitchell DK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA., Rhodes SD; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA., Angus SP; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Department of Pharmacology and Toxicology, and., Clapp DW; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jul 01; Vol. 135 (13). Date of Electronic Publication: 2025 Jul 01 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
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  Data: <searchLink fieldCode="AU" term="%22Park+SJ%22">Park SJ</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Research Institute for Korean Medicine, Pusan National University, Yangsan-si, South Korea.<br /><searchLink fieldCode="AU" term="%22Lukkes+JL%22">Lukkes JL</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Chan+KK%22">Chan KK</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Drozd+HP%22">Drozd HP</searchLink>; Medical Scientist Training Program.<br /><searchLink fieldCode="AU" term="%22Burgin+CB%22">Burgin CB</searchLink>; Department of Dermatology, and.<br /><searchLink fieldCode="AU" term="%22Qian+S%22">Qian S</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+MM%22">Sullivan MM</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Guevara+CG%22">Guevara CG</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Cunningham+N%22">Cunningham N</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Arenas+S%22">Arenas S</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Collins+MA%22">Collins MA</searchLink>; Department of Psychiatry.<br /><searchLink fieldCode="AU" term="%22Zucker+J%22">Zucker J</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Won+J%22">Won J</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Smith+A%22">Smith A</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+DK%22">Mitchell DK</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Rhodes+SD%22">Rhodes SD</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Angus+SP%22">Angus SP</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Department of Pharmacology and Toxicology, and.<br /><searchLink fieldCode="AU" term="%22Clapp+DW%22">Clapp DW</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Division of Hematology-Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Jul 01; Vol. 135 (13). <i>Date of Electronic Publication: </i>2025 Jul 01 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI188932
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        Text: English
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      – TitleFull: A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
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              Text: 2025 Jul 01
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