Fabrication of RIG-I-Activating Nanoparticles for Intratumoral Immunotherapy via Flash Nanoprecipitation.

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Title: Fabrication of RIG-I-Activating Nanoparticles for Intratumoral Immunotherapy via Flash Nanoprecipitation.
Authors: Stone PT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Kwiatkowski AJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Roth EW; NUANCE BioCryo, Northwestern University, Evanston, Illinois 60208, United States., Fedorova O; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States., Pyle AM; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States.; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States., Wilson JT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Nanoscale Science and Engineering, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.
Source: Molecular pharmaceutics [Mol Pharm] 2025 Aug 04; Vol. 22 (8), pp. 4597-4611. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Stone+PT%22">Stone PT</searchLink>; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.<br /><searchLink fieldCode="AU" term="%22Kwiatkowski+AJ%22">Kwiatkowski AJ</searchLink>; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.<br /><searchLink fieldCode="AU" term="%22Roth+EW%22">Roth EW</searchLink>; NUANCE BioCryo, Northwestern University, Evanston, Illinois 60208, United States.<br /><searchLink fieldCode="AU" term="%22Fedorova+O%22">Fedorova O</searchLink>; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States.<br /><searchLink fieldCode="AU" term="%22Pyle+AM%22">Pyle AM</searchLink>; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, United States.; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States.; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.<br /><searchLink fieldCode="AU" term="%22Wilson+JT%22">Wilson JT</searchLink>; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Nanoscale Science and Engineering, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.
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  Data: <searchLink fieldCode="JN" term="%22101197791%22">Molecular pharmaceutics</searchLink> [Mol Pharm] 2025 Aug 04; Vol. 22 (8), pp. 4597-4611. <i>Date of Electronic Publication: </i>2025 Jul 01.
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        Value: 10.1021/acs.molpharmaceut.5c00125
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      – TitleFull: Fabrication of RIG-I-Activating Nanoparticles for Intratumoral Immunotherapy via Flash Nanoprecipitation.
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              Text: 2025 Aug 04
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