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Impact of transplant conditioning, NPM1 mutations, and measurable residual disease in FLT3-ITD acute myeloid leukemia.

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Title: Impact of transplant conditioning, NPM1 mutations, and measurable residual disease in FLT3-ITD acute myeloid leukemia.
Authors: Levis MJ; Division of Hematologic Malignancies and Bone Marrow Transplant, Department of Oncology, Johns Hopkins University, Baltimore, MD., Hamadani M; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI., Logan BR; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI., Jones RJ; Division of Hematologic Malignancies and Bone Marrow Transplant, Department of Oncology, Johns Hopkins University, Baltimore, MD., Singh AK; Division of Hematologic Malignancies and Cellular Therapeutics, University of Kansas, Kansas City, KS., Litzow MR; Division of Hematology and Transplant Center, Mayo Clinic, Rochester, MN., Wingard JR; Department of Medicine, University of Florida, Gainesville, FL., Papadopoulos EB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Perl AE; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA., Soiffer RJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Ustun C; Division of Hematology Oncology and Cell Therapy, Rush University Medical Center, Chicago, IL., Oshima MU; Cancer Research Division, Fred Hutchinson Cancer Center, Seattle, WA., Uy GL; Department of Medicine, Washington University, St. Louis, MO., Waller EK; Department of Hematology and Medical Oncology, Emory University, Atlanta, GA., Vasu S; Division of Hematology, The Ohio State University, Columbus, OH., Solh M; Bone Marrow Transplant, Acute Leukemia, and Immunotherapy Program, Northside Hospital Cancer Institute, Atlanta, GA., Mishra A; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL., Muffly LS; Division of Blood and Marrow Transplantation, Stanford University, Stanford, CA., Kim HJ; Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Stelljes M; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany., Najima Y; Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan., Onozawa M; Department of Hematology, Hokkaido University Hospital, Sapporo, Japan., Thomson K; Department of Hematology, University College Hospital, London, United Kingdom., Chen C; Astellas Pharma Global Development, Inc, Northbrook, IL., Hasabou N; Astellas Pharma Global Development, Inc, Northbrook, IL., Rosales M; Astellas Pharma Global Development, Inc, Northbrook, IL., Hill JE; Astellas Pharma Global Development, Inc, Northbrook, IL., Gill SC; Astellas Pharma Global Development, Inc, Northbrook, IL., Nuthethi R; Astellas Pharma Global Development, Inc, Northbrook, IL., King D; The Emmes Company, Rockville, MD., Mendizabal A; The Emmes Company, Rockville, MD., Devine SM; National Marrow Donor Program, Minneapolis, MN., Horowitz MM; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI., Chen YB; Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA.
Source: Blood advances [Blood Adv] 2025 Oct 28; Vol. 9 (20), pp. 5123-5133.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: Impact of transplant conditioning, NPM1 mutations, and measurable residual disease in FLT3-ITD acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Levis+MJ%22">Levis MJ</searchLink>; Division of Hematologic Malignancies and Bone Marrow Transplant, Department of Oncology, Johns Hopkins University, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Hamadani+M%22">Hamadani M</searchLink>; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Logan+BR%22">Logan BR</searchLink>; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Jones+RJ%22">Jones RJ</searchLink>; Division of Hematologic Malignancies and Bone Marrow Transplant, Department of Oncology, Johns Hopkins University, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Singh+AK%22">Singh AK</searchLink>; Division of Hematologic Malignancies and Cellular Therapeutics, University of Kansas, Kansas City, KS.<br /><searchLink fieldCode="AU" term="%22Litzow+MR%22">Litzow MR</searchLink>; Division of Hematology and Transplant Center, Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Wingard+JR%22">Wingard JR</searchLink>; Department of Medicine, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+EB%22">Papadopoulos EB</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Perl+AE%22">Perl AE</searchLink>; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Soiffer+RJ%22">Soiffer RJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Ustun+C%22">Ustun C</searchLink>; Division of Hematology Oncology and Cell Therapy, Rush University Medical Center, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Oshima+MU%22">Oshima MU</searchLink>; Cancer Research Division, Fred Hutchinson Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Uy+GL%22">Uy GL</searchLink>; Department of Medicine, Washington University, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Waller+EK%22">Waller EK</searchLink>; Department of Hematology and Medical Oncology, Emory University, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Vasu+S%22">Vasu S</searchLink>; Division of Hematology, The Ohio State University, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Solh+M%22">Solh M</searchLink>; Bone Marrow Transplant, Acute Leukemia, and Immunotherapy Program, Northside Hospital Cancer Institute, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Mishra+A%22">Mishra A</searchLink>; Department of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Muffly+LS%22">Muffly LS</searchLink>; Division of Blood and Marrow Transplantation, Stanford University, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Stelljes+M%22">Stelljes M</searchLink>; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Najima+Y%22">Najima Y</searchLink>; Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Onozawa+M%22">Onozawa M</searchLink>; Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Thomson+K%22">Thomson K</searchLink>; Department of Hematology, University College Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22Hasabou+N%22">Hasabou N</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22Rosales+M%22">Rosales M</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22Hill+JE%22">Hill JE</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22Gill+SC%22">Gill SC</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22Nuthethi+R%22">Nuthethi R</searchLink>; Astellas Pharma Global Development, Inc, Northbrook, IL.<br /><searchLink fieldCode="AU" term="%22King+D%22">King D</searchLink>; The Emmes Company, Rockville, MD.<br /><searchLink fieldCode="AU" term="%22Mendizabal+A%22">Mendizabal A</searchLink>; The Emmes Company, Rockville, MD.<br /><searchLink fieldCode="AU" term="%22Devine+SM%22">Devine SM</searchLink>; National Marrow Donor Program, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Horowitz+MM%22">Horowitz MM</searchLink>; Division of Hematology and Oncology, Department of Medicine, Center for International Blood and Marrow Transplant Research/Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Chen+YB%22">Chen YB</searchLink>; Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA.
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