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Tumor-migrating peripheral Foxp3-high regulatory T cells drive poor prognosis in HCC.

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Title: Tumor-migrating peripheral Foxp3-high regulatory T cells drive poor prognosis in HCC.
Authors: Huang CH; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Liver Research Center, Chang Gung Memorial Hospital, Linkou., Ku WT; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Mahalingam J; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; Institute for Healthcare Education and Translational Sciences (IHETS), W. Marredpally, Secunderabad, Telangana, India., Wu CH; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan., Wu TH; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Division of Liver & Transplantation Surgery, Department of General Surgery, Chang-Gung Memorial Hospital, Linkou Medical Center, Guishan, Taoyuan, Taiwan., Fang JH; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan., Su CW; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Lin PT; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Peng CW; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Yang CK; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Hematology-Oncology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan., Teng W; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Jeng WJ; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Chen WT; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Lin CC; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Gastroenterology and Hepatology, New Taipei Municipal Tucheng Hospital (Built and Operated by Chang Gung Memorial Hospital), New Taipei City, Taiwan., Lin SM; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Sheen IS; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan., Lin YC; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Hematology-Oncology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan., Lin CY; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.
Source: Hepatology (Baltimore, Md.) [Hepatology] 2026 Jun 01; Vol. 83 (6), pp. 1398-1415. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor-migrating peripheral Foxp3-high regulatory T cells drive poor prognosis in HCC.
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  Data: <searchLink fieldCode="AU" term="%22Huang+CH%22">Huang CH</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Liver Research Center, Chang Gung Memorial Hospital, Linkou.<br /><searchLink fieldCode="AU" term="%22Ku+WT%22">Ku WT</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Mahalingam+J%22">Mahalingam J</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; Institute for Healthcare Education and Translational Sciences (IHETS), W. Marredpally, Secunderabad, Telangana, India.<br /><searchLink fieldCode="AU" term="%22Wu+CH%22">Wu CH</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+TH%22">Wu TH</searchLink>; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Division of Liver & Transplantation Surgery, Department of General Surgery, Chang-Gung Memorial Hospital, Linkou Medical Center, Guishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fang+JH%22">Fang JH</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+CW%22">Su CW</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PT%22">Lin PT</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+CW%22">Peng CW</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+CK%22">Yang CK</searchLink>; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Hematology-Oncology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Teng+W%22">Teng W</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jeng+WJ%22">Jeng WJ</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WT%22">Chen WT</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Gastroenterology and Hepatology, New Taipei Municipal Tucheng Hospital (Built and Operated by Chang Gung Memorial Hospital), New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SM%22">Lin SM</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sheen+IS%22">Sheen IS</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YC%22">Lin YC</searchLink>; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.; Department of Hematology-Oncology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Division of Hepatology, Department of Gastroenterology-Hepatology Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%228302946%22">Hepatology (Baltimore, Md.)</searchLink> [Hepatology] 2026 Jun 01; Vol. 83 (6), pp. 1398-1415. <i>Date of Electronic Publication: </i>2025 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8302946 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-3350 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202709139%22">02709139 </searchLink><i>NLM ISO Abbreviation: </i>Hepatology <i>Subsets: </i>MEDLINE
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        Value: 10.1097/HEP.0000000000001428
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