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Single nucleus RNA-seq reveals the process from onset to chronic kidney disease in IgA nephropathy.

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Title: Single nucleus RNA-seq reveals the process from onset to chronic kidney disease in IgA nephropathy.
Authors: You JP; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Cheng GY; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Zhang XX; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Wang Z; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Liu C; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Ning W; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Liu YR; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Hu HM; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Zhai YL; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China., Qi YY; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China. qqyyiillyy@126.com.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. qqyyiillyy@126.com.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China. qqyyiillyy@126.com., Zhao ZZ; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.
Source: Scientific reports [Sci Rep] 2025 Jul 02; Vol. 15 (1), pp. 22780. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single nucleus RNA-seq reveals the process from onset to chronic kidney disease in IgA nephropathy.
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  Data: <searchLink fieldCode="AU" term="%22You+JP%22">You JP</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Cheng+GY%22">Cheng GY</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+XX%22">Zhang XX</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ning+W%22">Ning W</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+YR%22">Liu YR</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Hu+HM%22">Hu HM</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhai+YL%22">Zhai YL</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Qi+YY%22">Qi YY</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China. qqyyiillyy@126.com.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. qqyyiillyy@126.com.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China. qqyyiillyy@126.com.<br /><searchLink fieldCode="AU" term="%22Zhao+ZZ%22">Zhao ZZ</searchLink>; Department of Nephrology, Nephrology Hospital, The First Affiliated Hospital of Zhengzhou University,Institute of Nephrology, Zhengzhou University, No.1, Jianshe Road, Erqi District, Zhengzhou, 450052, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.; Zhengzhou University, Zhengzhou, 450001, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.; Laboratory of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of China. zhanzhengzhao@zzu.edu.cn.
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