Cell-specific mechanisms drive connectivity across the time course of Huntington's disease.

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Title: Cell-specific mechanisms drive connectivity across the time course of Huntington's disease.
Authors: Estevez-Fraga C; Department of Neurodegenerative Disease, University College London, London, UK. estevezfragacarlos@gmail.com., Sebenius I; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK., Hansen JY; McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University, Montréal, QC, Canada., Hänisch B; Department of Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.; German Centre for Mental Health, Tübingen, Germany.; Max Planck School of Cognition, Leipzig, Germany., Zeun P; Southampton General Hospital, Southampton, UK., Scahill RI; Department of Neurodegenerative Disease, University College London, London, UK., Gregory S; Department of Neurodegenerative Disease, University College London, London, UK., Johnson EB; Department for Science Innovation and Technology, London, UK., Wild EJ; Department of Neurodegenerative Disease, University College London, London, UK., Byrne LM; Department of Neurodegenerative Disease, University College London, London, UK., Durr A; Sorbonne Université, Paris Brain Institute (ICM), AP-HP, Inserm, CNRS, Pitié-Salpêtrière University Hospital, Paris, France., Landwehrmeyer B; University of Ulm, Ulm, Germany., Leavitt BR; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada.; UBC Children's Hospital, Vancouver, BC, Canada., Misic B; McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University, Montréal, QC, Canada., Valk SL; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany.; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Otto Hahn Group 'Cognitive Neurogenetics', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany., Rees G; Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, UK., Tabrizi SJ; Department of Neurodegenerative Disease, University College London, London, UK. s.tabrizi@ucl.ac.uk., McColgan P; Department of Neurodegenerative Disease, University College London, London, UK.; Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5519. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Cell-specific mechanisms drive connectivity across the time course of Huntington's disease.
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  Data: <searchLink fieldCode="AU" term="%22Estevez-Fraga+C%22">Estevez-Fraga C</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK. estevezfragacarlos@gmail.com.<br /><searchLink fieldCode="AU" term="%22Sebenius+I%22">Sebenius I</searchLink>; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hansen+JY%22">Hansen JY</searchLink>; McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Hänisch+B%22">Hänisch B</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.; German Centre for Mental Health, Tübingen, Germany.; Max Planck School of Cognition, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Zeun+P%22">Zeun P</searchLink>; Southampton General Hospital, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Scahill+RI%22">Scahill RI</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gregory+S%22">Gregory S</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Johnson+EB%22">Johnson EB</searchLink>; Department for Science Innovation and Technology, London, UK.<br /><searchLink fieldCode="AU" term="%22Wild+EJ%22">Wild EJ</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Byrne+LM%22">Byrne LM</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Durr+A%22">Durr A</searchLink>; Sorbonne Université, Paris Brain Institute (ICM), AP-HP, Inserm, CNRS, Pitié-Salpêtrière University Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Landwehrmeyer+B%22">Landwehrmeyer B</searchLink>; University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Leavitt+BR%22">Leavitt BR</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada.; UBC Children's Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Misic+B%22">Misic B</searchLink>; McConnell Brain Imaging Centre, Montréal Neurological Institute, McGill University, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Valk+SL%22">Valk SL</searchLink>; Institute of Neuroscience and Medicine, Research Centre Jülich, Jülich, Germany.; Institute of Systems Neuroscience, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Otto Hahn Group 'Cognitive Neurogenetics', Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Rees+G%22">Rees G</searchLink>; Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Tabrizi+SJ%22">Tabrizi SJ</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK. s.tabrizi@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22McColgan+P%22">McColgan P</searchLink>; Department of Neurodegenerative Disease, University College London, London, UK.; Roche Pharma Research and Early Development (pRED), F. Hoffmann-La Roche Ltd., Basel, Switzerland.
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