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Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight.

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Title: Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight.
Authors: Gregorova M; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Santopaolo M; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Garner LC; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Hayati RF; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Diamond D; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Ramamurthy N; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tran VT; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Nguyen NM; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Heesom KJ; Bristol Proteomics Facility, School of Biochemistry, University of Bristol, Bristol, UK., Nguyen VL; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Jones E; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Nsubuga M; Jean Golding Institute, University of Bristol, Bristol, UK., Luscombe C; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Vo HTM; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Ho CQ; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Nguyen CTX; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Dong TTH; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Huynh DTL; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam., Cao TT; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Klenerman P; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Yacoub S; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Oxford University, Oxford, UK., Rivino L; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK. laura.rivino@bristol.ac.uk.
Source: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5569. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight.
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  Data: <searchLink fieldCode="AU" term="%22Gregorova+M%22">Gregorova M</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Santopaolo+M%22">Santopaolo M</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Garner+LC%22">Garner LC</searchLink>; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hayati+RF%22">Hayati RF</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Diamond+D%22">Diamond D</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Ramamurthy+N%22">Ramamurthy N</searchLink>; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tran+VT%22">Tran VT</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Nguyen+NM%22">Nguyen NM</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Heesom+KJ%22">Heesom KJ</searchLink>; Bristol Proteomics Facility, School of Biochemistry, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Nguyen+VL%22">Nguyen VL</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Jones+E%22">Jones E</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Nsubuga+M%22">Nsubuga M</searchLink>; Jean Golding Institute, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Luscombe+C%22">Luscombe C</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Vo+HTM%22">Vo HTM</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Ho+CQ%22">Ho CQ</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Nguyen+CTX%22">Nguyen CTX</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Dong+TTH%22">Dong TTH</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Huynh+DTL%22">Huynh DTL</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Cao+TT%22">Cao TT</searchLink>; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.<br /><searchLink fieldCode="AU" term="%22Davidson+AD%22">Davidson AD</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Translational Gastroenterology and Liver Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Yacoub+S%22">Yacoub S</searchLink>; Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.; Centre for Tropical Medicine and Global Health, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rivino+L%22">Rivino L</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK. laura.rivino@bristol.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5569. <i>Date of Electronic Publication: </i>2025 Jul 01.
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