Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.

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Title: Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.
Authors: Krick KE; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Weekman EM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: eweekman@iu.edu., Johnson SN; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Sudduth TL; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Rogers CB; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA., Nicolayson EJ; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Kleinhenz MT; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Wilcock DM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: dwilcock@iu.edu.
Source: Neurobiology of disease [Neurobiol Dis] 2025 Sep; Vol. 213, pp. 107013. Date of Electronic Publication: 2025 Jun 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
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  Data: Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.
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  Data: <searchLink fieldCode="AU" term="%22Krick+KE%22">Krick KE</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Weekman+EM%22">Weekman EM</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: eweekman@iu.edu.<br /><searchLink fieldCode="AU" term="%22Johnson+SN%22">Johnson SN</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Sudduth+TL%22">Sudduth TL</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+CB%22">Rogers CB</searchLink>; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.<br /><searchLink fieldCode="AU" term="%22Nicolayson+EJ%22">Nicolayson EJ</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Kleinhenz+MT%22">Kleinhenz MT</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Wilcock+DM%22">Wilcock DM</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA. Electronic address: dwilcock@iu.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9500169 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-953X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209699961%22">09699961 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.nbd.2025.107013
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        Text: English
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      – TitleFull: Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.
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