Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans.

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Title: Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans.
Authors: Hu IM; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands., Molenaars M; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Jaspers YRJ; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands., Schomakers BV; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands.; Core Facility Metabolomics, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands., van Weeghel M; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands.; Core Facility Metabolomics, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands., Bakker A; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands., Modder M; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands., Dewulf JP; Department of Biochemistry, de Duve Institute, UCLouvain, Brussels, Belgium., Bommer GT; Department of Biochemistry, de Duve Institute, UCLouvain, Brussels, Belgium., Gao AW; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands., Janssens GE; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands., Houtkooper RH; Laboratory Genetic Metabolic Diseases, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands. r.h.houtkooper@amsterdamumc.nl.; Amsterdam Gastroenterology Endocrinology and Metabolism Institute, Amsterdam, The Netherlands. r.h.houtkooper@amsterdamumc.nl.; Amsterdam Cardiovascular Sciences Institute, Amsterdam, The Netherlands. r.h.houtkooper@amsterdamumc.nl.
Source: Nature communications [Nat Commun] 2025 Jul 02; Vol. 16 (1), pp. 6083. Date of Electronic Publication: 2025 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-61433-6