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Case Report: Failure of eculizumab to block complement to prevent relapse of anti-phospholipid syndrome in kidney transplant recipient.

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Title: Case Report: Failure of eculizumab to block complement to prevent relapse of anti-phospholipid syndrome in kidney transplant recipient.
Authors: Laban T; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Pigneur F; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe hospitalo-universitaire Chenevier Mondor, Radiology Department, Créteil, France., Guillaud C; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Dragon Durey MA; Université Paris Cité, INSERM UMRS 1138, Centre de Recherche des Cordeliers, Assistance Publique Hôpitaux de Paris (AP-HPP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France., Hamidi H; Université Paris Cité, INSERM UMRS 1138, Centre de Recherche des Cordeliers, Assistance Publique Hôpitaux de Paris (AP-HPP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France., Pilon C; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Michel M; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Joher N; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Grimbert P; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Sakhi H; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Morel A; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France., Matignon M; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.
Source: Frontiers in nephrology [Front Nephrol] 2025 Jun 18; Vol. 5, pp. 1572641. Date of Electronic Publication: 2025 Jun 18 (Print Publication: 2025).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918469487906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2813-0626 (Electronic) Linking ISSN: 28130626 NLM ISO Abbreviation: Front Nephrol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Case Report: Failure of eculizumab to block complement to prevent relapse of anti-phospholipid syndrome in kidney transplant recipient.
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  Data: <searchLink fieldCode="AU" term="%22Laban+T%22">Laban T</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Pigneur+F%22">Pigneur F</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe hospitalo-universitaire Chenevier Mondor, Radiology Department, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Guillaud+C%22">Guillaud C</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Dragon+Durey+MA%22">Dragon Durey MA</searchLink>; Université Paris Cité, INSERM UMRS 1138, Centre de Recherche des Cordeliers, Assistance Publique Hôpitaux de Paris (AP-HPP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Hamidi+H%22">Hamidi H</searchLink>; Université Paris Cité, INSERM UMRS 1138, Centre de Recherche des Cordeliers, Assistance Publique Hôpitaux de Paris (AP-HPP), Groupe Hospitalier Paris Centre, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pilon+C%22">Pilon C</searchLink>; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Michel+M%22">Michel M</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Joher+N%22">Joher N</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Grimbert+P%22">Grimbert P</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Sakhi+H%22">Sakhi H</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Internal Medicine Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Morel+A%22">Morel A</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.<br /><searchLink fieldCode="AU" term="%22Matignon+M%22">Matignon M</searchLink>; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Nephrology and Renal Transplantation Department, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.; Univ Paris Est Creteil, INSERM IMRB U955, Créteil, France.; Assistance Publique Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Chenevier Mondor, Centre d'Investigation Clinique Biotherapy, Fédération Hospitalo-Universitaire 'Innovative Therapy for Immune Disorders,', Créteil, France.
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