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Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.

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Title: Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.
Authors: Karafin MS; Department of Pathology and Laboratory Medicine, University of North Carolina (UNC) at Chapel Hill, Chapel Hill, North Carolina, USA., Grier AL; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Fasano RM; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Ilich A; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA., Wichlan D; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA., Chang A; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA., James SM; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Butler HE; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Kolupaev O; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA., Caughey MC; Joint Department of Biomedical Engineering, UNC and North Carolina State University, Chapel Hill, North Carolina, USA., Stephenson DJ; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Reisz JA; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Key NS; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA., Field JJ; Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin (MCW), Milwaukee, Wisconsin, USA., Little JA; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA., Spitalnik SL; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jul 03; Vol. 135 (17). Date of Electronic Publication: 2025 Jul 03 (Print Publication: 2025).
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.
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  Data: <searchLink fieldCode="AU" term="%22Karafin+MS%22">Karafin MS</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina (UNC) at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Grier+AL%22">Grier AL</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Fasano+RM%22">Fasano RM</searchLink>; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Ilich+A%22">Ilich A</searchLink>; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Wichlan+D%22">Wichlan D</searchLink>; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Chang+A%22">Chang A</searchLink>; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22James+SM%22">James SM</searchLink>; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Butler+HE%22">Butler HE</searchLink>; Center for Transfusion Medicine and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Kolupaev+O%22">Kolupaev O</searchLink>; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Caughey+MC%22">Caughey MC</searchLink>; Joint Department of Biomedical Engineering, UNC and North Carolina State University, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Stephenson+DJ%22">Stephenson DJ</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Reisz+JA%22">Reisz JA</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Key+NS%22">Key NS</searchLink>; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Field+JJ%22">Field JJ</searchLink>; Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin (MCW), Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Little+JA%22">Little JA</searchLink>; Division of Hematology and Blood Research Center, Department of Medicine, UNC at Chapel Hill, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Spitalnik+SL%22">Spitalnik SL</searchLink>; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Jul 03; Vol. 135 (17). <i>Date of Electronic Publication: </i>2025 Jul 03 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI192920
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      – TitleFull: Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.
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