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Relative importance of the anti-apoptotic versus apoptosis-unrelated functions of MCL-1 in vivo.

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Title: Relative importance of the anti-apoptotic versus apoptosis-unrelated functions of MCL-1 in vivo.
Authors: Brinkmann K; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., McArthur K; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia., Malelang S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Gibson L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Tee A; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Elahee Doomun SN; Metabolomics Australia, Bio21 Institute, University of Melbourne, Melbourne, Australia., Rowe CL; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia., Arandjelovic P; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Marchingo JM; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., D'Silva D; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Bachem A; Department of Microbiology and Immunology, Peter Doherty Institute, University of Melbourne, Melbourne, Australia., Monard S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Whelan LG; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Dewson G; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Putoczki TL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Bouillet P; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Fu NY; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore., Brown KK; Peter MacCallum Cancer Centre, Melbourne, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Australia., Kueh AJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia., Wimmer VC; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia., Thomas T; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Voss AK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia., Strasser A; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.
Source: Science (New York, N.Y.) [Science] 2025 Sep 04; Vol. 389 (6764), pp. 1003-1011. Date of Electronic Publication: 2025 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: Relative importance of the anti-apoptotic versus apoptosis-unrelated functions of MCL-1 in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Brinkmann+K%22">Brinkmann K</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22McArthur+K%22">McArthur K</searchLink>; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Malelang+S%22">Malelang S</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Gibson+L%22">Gibson L</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Tee+A%22">Tee A</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Elahee+Doomun+SN%22">Elahee Doomun SN</searchLink>; Metabolomics Australia, Bio21 Institute, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Rowe+CL%22">Rowe CL</searchLink>; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Arandjelovic+P%22">Arandjelovic P</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Marchingo+JM%22">Marchingo JM</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22D'Silva+D%22">D'Silva D</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Bachem+A%22">Bachem A</searchLink>; 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Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Fu+NY%22">Fu NY</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Brown+KK%22">Brown KK</searchLink>; Peter MacCallum Cancer Centre, Melbourne, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Kueh+AJ%22">Kueh AJ</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Wimmer+VC%22">Wimmer VC</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Herold+MJ%22">Herold MJ</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Thomas+T%22">Thomas T</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Voss+AK%22">Voss AK</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Strasser+A%22">Strasser A</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Australia.
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