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The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine, and durvalumab: a large, real-life, worldwide population.

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Title: The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine, and durvalumab: a large, real-life, worldwide population.
Authors: Rimini M; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Fornaro L; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Lo Prinzi F; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma 200-00128, Italy., Rizzato MD; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Saborowski A; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Antonuzzo L; Clinical Oncology Unit, Careggi University Hospital, and Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy., Rossari F; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Satake T; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Peeters F; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium., Vivaldi C; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Pressiani T; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy., Lucchetti J; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma 200-00128, Italy., Kim JW; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do 13620, Republic of Korea., Abidoye O; Department of Internal Medicine, Mayo Clinic, Phoenix, AZ, United States., Rapposelli IG; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori,' Meldola, Italy., Tamberi S; Medical Oncology, Santa Maria Delle Croci Hospital, Ravenna AUSL Romagna, Ravenna, Italy., Finkelmeier F; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany., Giordano G; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy., Nichetti F; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Jae Chon H; Division of Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea., Braconi C; Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, University of Glasgow (School of Cancer Sciences), Glasgow, United Kingdom., Qaisar A; Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, University of Glasgow (School of Cancer Sciences), Glasgow, United Kingdom., Pirrone C; Medical Oncology Unit 1, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Castet F; Gastrointestinal and Endocrine Tumor Unit, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Tamburini E; Oncology Department and Palliative Care, Cardinale Panico Tricase City Hospital, Tricase 73039, Italy., Yoo C; ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Parisi A; Clinica Oncologica e Centro Regionale di Genetica Oncologica, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona 60126, Italy., Diana A; Oncology Unit, Ospedale del Mare, Napoli, Italy., Scartozzi M; Medical Oncology, University and University Hospital, Cagliari, Italy., Prager GW; Department of Medicine I, Clinical Division of Oncology, Medical University Vienna, Vienna, Austria., Avallone A; Clinical Experimental Abdominal Oncology Unit, Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale, Naples 80131, Italy., Corallo S; Medical Oncology Unit, IRCCS Policlinico San Matteo, Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy., Schirripa M; Medical Oncology Unit, Department of Oncology and Hematology, Belcolle Hospital, Viterbo, Italy., Kim IH; Division of Oncology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea., Perkhofer L; Internal Medicine 1, University Hospital Ulm, Ulm, Germany.; Institute of Molecular Oncology and Stem Cell Biology, Ulm University Hospital, Ulm, Germany., Oneda E; Dipartimento di Oncologia Medica, Fondazione Poliambulanza, Brescia, Italy., Verrico M; UOC Oncologia A, Department of Hematology, Oncology and Dermatology, Policlinico Umberto I University Hospital, Sapienza University of Rome, Viale Regina Elena, Rome 324, 00161, Italy., Adeva J; Spanish Society of Medical Oncology (SEOM), 12 de Octubre University Hospital, Madrid, Spain., Chan SL; State Key Laboratory of Translational Oncology, Department of Clinical Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Spinelli GP; UOC Oncologia Territoriale, Polo Pontino, La Sapienza Università Di Roma, Latina, Italy., Personeni N; Medical Oncology Unit, P.O. Manerbio-ASST Garda, Manerbio, Brescia 25025, Italy., Garajova I; Medical Oncology Unit, University Hospital of Parma, Parma 43126, Italy., Rodriquenz MG; Oncology Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza,' San Giovanni Rotondo, Italy., Leo S; Division of Oncology, Vito Fazzi Hospital, Lecce, Italy., Alvim CM; Medical Oncology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon 1649-035, Portugal., Roque R; Portuguese Institute of Oncology of Coimbra, Coimbra 3000-075, Portugal., Farinea G; Department of Oncology, University of Turin, San Luigi Hospital, Turin, Italy., Salani F; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., De Rosa A; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy., Lavacchi D; Clinical Oncology Unit, Careggi University Hospital, and Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Camera S; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Ikeda M; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Dekervel J; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium., Niger M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Balsano R; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Tonini G; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Roma 21-00128, Italy., Kang M; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do 13620, Republic of Korea., Bekaii-Saab T; Department of Internal Medicine, Mayo Clinic, Phoenix, AZ, United States., Esposito L; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori,' Meldola, Italy., Boccaccino A; Medical Oncology, Santa Maria Delle Croci Hospital, Ravenna AUSL Romagna, Ravenna, Italy., Himmelsbach V; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany., Landriscina M; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy., Djaballah SA; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Zanuso V; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Malapelle U; Department of Public Health, University Federico II, Naples 80131, Italy., Pepe F; Department of Public Health, University Federico II, Naples 80131, Italy., Masi G; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Vogel A; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Longo Family Chair in Liver Cancer Research, Division of Gastroenterology and Hepatology, Toronto General Hospital, Medical Oncology, Princess Margaret Cancer Centre, Schwartz Reisman Liver Research Centre, Toronto, Canada., Lonardi S; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Rimassa L; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Casadei-Gardini A; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.
Source: Journal of the National Cancer Institute [J Natl Cancer Inst] 2025 Oct 01; Vol. 117 (10), pp. 2029-2043.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine, and durvalumab: a large, real-life, worldwide population.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Rimini+M%22">Rimini M</searchLink>; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fornaro+L%22">Fornaro L</searchLink>; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Lo+Prinzi+F%22">Lo Prinzi F</searchLink>; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma 200-00128, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzato+MD%22">Rizzato MD</searchLink>; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Saborowski+A%22">Saborowski A</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Antonuzzo+L%22">Antonuzzo L</searchLink>; Clinical Oncology Unit, Careggi University Hospital, and Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Rossari+F%22">Rossari F</searchLink>; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Satake+T%22">Satake T</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.<br /><searchLink fieldCode="AU" term="%22Peeters+F%22">Peeters F</searchLink>; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vivaldi+C%22">Vivaldi C</searchLink>; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Pressiani+T%22">Pressiani T</searchLink>; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Lucchetti+J%22">Lucchetti J</searchLink>; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma 200-00128, Italy.<br /><searchLink fieldCode="AU" term="%22Kim+JW%22">Kim JW</searchLink>; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do 13620, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Abidoye+O%22">Abidoye O</searchLink>; Department of Internal Medicine, Mayo Clinic, Phoenix, AZ, United States.<br /><searchLink fieldCode="AU" term="%22Rapposelli+IG%22">Rapposelli IG</searchLink>; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori,' Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Tamberi+S%22">Tamberi S</searchLink>; Medical Oncology, Santa Maria Delle Croci Hospital, Ravenna AUSL Romagna, Ravenna, Italy.<br /><searchLink fieldCode="AU" term="%22Finkelmeier+F%22">Finkelmeier F</searchLink>; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Giordano+G%22">Giordano G</searchLink>; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Nichetti+F%22">Nichetti F</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Jae+Chon+H%22">Jae Chon H</searchLink>; Division of Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Braconi+C%22">Braconi C</searchLink>; Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, University of Glasgow (School of Cancer Sciences), Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Qaisar+A%22">Qaisar A</searchLink>; Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, University of Glasgow (School of Cancer Sciences), Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pirrone+C%22">Pirrone C</searchLink>; Medical Oncology Unit 1, IRCCS Ospedale Policlinico San Martino, Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Castet+F%22">Castet F</searchLink>; Gastrointestinal and Endocrine Tumor Unit, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tamburini+E%22">Tamburini E</searchLink>; Oncology Department and Palliative Care, Cardinale Panico Tricase City Hospital, Tricase 73039, Italy.<br /><searchLink fieldCode="AU" term="%22Yoo+C%22">Yoo C</searchLink>; ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Parisi+A%22">Parisi A</searchLink>; Clinica Oncologica e Centro Regionale di Genetica Oncologica, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona 60126, Italy.<br /><searchLink fieldCode="AU" term="%22Diana+A%22">Diana A</searchLink>; Oncology Unit, Ospedale del Mare, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Scartozzi+M%22">Scartozzi M</searchLink>; Medical Oncology, University and University Hospital, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Prager+GW%22">Prager GW</searchLink>; Department of Medicine I, Clinical Division of Oncology, Medical University Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Avallone+A%22">Avallone A</searchLink>; Clinical Experimental Abdominal Oncology Unit, Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale, Naples 80131, Italy.<br /><searchLink fieldCode="AU" term="%22Corallo+S%22">Corallo S</searchLink>; Medical Oncology Unit, IRCCS Policlinico San Matteo, Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Schirripa+M%22">Schirripa M</searchLink>; Medical Oncology Unit, Department of Oncology and Hematology, Belcolle Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Kim+IH%22">Kim IH</searchLink>; Division of Oncology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Perkhofer+L%22">Perkhofer L</searchLink>; Internal Medicine 1, University Hospital Ulm, Ulm, Germany.; Institute of Molecular Oncology and Stem Cell Biology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Oneda+E%22">Oneda E</searchLink>; Dipartimento di Oncologia Medica, Fondazione Poliambulanza, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Verrico+M%22">Verrico M</searchLink>; UOC Oncologia A, Department of Hematology, Oncology and Dermatology, Policlinico Umberto I University Hospital, Sapienza University of Rome, Viale Regina Elena, Rome 324, 00161, Italy.<br /><searchLink fieldCode="AU" term="%22Adeva+J%22">Adeva J</searchLink>; Spanish Society of Medical Oncology (SEOM), 12 de Octubre University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Chan+SL%22">Chan SL</searchLink>; State Key Laboratory of Translational Oncology, Department of Clinical Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Spinelli+GP%22">Spinelli GP</searchLink>; UOC Oncologia Territoriale, Polo Pontino, La Sapienza Università Di Roma, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Personeni+N%22">Personeni N</searchLink>; Medical Oncology Unit, P.O. Manerbio-ASST Garda, Manerbio, Brescia 25025, Italy.<br /><searchLink fieldCode="AU" term="%22Garajova+I%22">Garajova I</searchLink>; Medical Oncology Unit, University Hospital of Parma, Parma 43126, Italy.<br /><searchLink fieldCode="AU" term="%22Rodriquenz+MG%22">Rodriquenz MG</searchLink>; Oncology Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza,' San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Leo+S%22">Leo S</searchLink>; Division of Oncology, Vito Fazzi Hospital, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Alvim+CM%22">Alvim CM</searchLink>; Medical Oncology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon 1649-035, Portugal.<br /><searchLink fieldCode="AU" term="%22Roque+R%22">Roque R</searchLink>; Portuguese Institute of Oncology of Coimbra, Coimbra 3000-075, Portugal.<br /><searchLink fieldCode="AU" term="%22Farinea+G%22">Farinea G</searchLink>; Department of Oncology, University of Turin, San Luigi Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Salani+F%22">Salani F</searchLink>; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22De+Rosa+A%22">De Rosa A</searchLink>; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Lavacchi+D%22">Lavacchi D</searchLink>; Clinical Oncology Unit, Careggi University Hospital, and Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Camera+S%22">Camera S</searchLink>; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ikeda+M%22">Ikeda M</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.<br /><searchLink fieldCode="AU" term="%22Dekervel+J%22">Dekervel J</searchLink>; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Niger+M%22">Niger M</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Balsano+R%22">Balsano R</searchLink>; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Tonini+G%22">Tonini G</searchLink>; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Roma 21-00128, Italy.<br /><searchLink fieldCode="AU" term="%22Kang+M%22">Kang M</searchLink>; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do 13620, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bekaii-Saab+T%22">Bekaii-Saab T</searchLink>; Department of Internal Medicine, Mayo Clinic, Phoenix, AZ, United States.<br /><searchLink fieldCode="AU" term="%22Esposito+L%22">Esposito L</searchLink>; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori,' Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Boccaccino+A%22">Boccaccino A</searchLink>; Medical Oncology, Santa Maria Delle Croci Hospital, Ravenna AUSL Romagna, Ravenna, Italy.<br /><searchLink fieldCode="AU" term="%22Himmelsbach+V%22">Himmelsbach V</searchLink>; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Landriscina+M%22">Landriscina M</searchLink>; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Djaballah+SA%22">Djaballah SA</searchLink>; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Zanuso+V%22">Zanuso V</searchLink>; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Malapelle+U%22">Malapelle U</searchLink>; Department of Public Health, University Federico II, Naples 80131, Italy.<br /><searchLink fieldCode="AU" term="%22Pepe+F%22">Pepe F</searchLink>; Department of Public Health, University Federico II, Naples 80131, Italy.<br /><searchLink fieldCode="AU" term="%22Masi+G%22">Masi G</searchLink>; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Vogel+A%22">Vogel A</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; Longo Family Chair in Liver Cancer Research, Division of Gastroenterology and Hepatology, Toronto General Hospital, Medical Oncology, Princess Margaret Cancer Centre, Schwartz Reisman Liver Research Centre, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Lonardi+S%22">Lonardi S</searchLink>; Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Rimassa+L%22">Rimassa L</searchLink>; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy.<br /><searchLink fieldCode="AU" term="%22Casadei-Gardini+A%22">Casadei-Gardini A</searchLink>; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.
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      – TitleFull: The impact of molecular alterations in patients with advanced biliary tract cancer receiving cisplatin, gemcitabine, and durvalumab: a large, real-life, worldwide population.
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          Dates:
            – D: 01
              M: 10
              Text: 2025 Oct 01
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1460-2105
          Numbering:
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              Value: 117
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Journal of the National Cancer Institute
              Type: main
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