CYP2C19 Phenotype, P2Y12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy.

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Title: CYP2C19 Phenotype, P2Y12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy.
Authors: Patel RC; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA., Thomas CD; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA., Rossi JS; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA., Franchi F; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA., Keeley EC; Division of Cardiovascular Medicine, College of Medicine University of Florida Gainesville FL USA., Beitelshees AL; Department of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD USA., Duarte JD; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA., Ortega-Paz L; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA., Kulick N; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA., Winget M; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA., Nguyen AB; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA., Yang WE; Department of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD USA., Venkatesh S; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA., Angiolillo DJ; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA., Cavallari LH; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA., Lee CR; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA., Stouffer GA; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2025 Jul 15; Vol. 14 (14), pp. e041634. Date of Electronic Publication: 2025 Jul 03.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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  Data: CYP2C19 Phenotype, P2Y<subscript>12</subscript> Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy.
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  Data: <searchLink fieldCode="AU" term="%22Patel+RC%22">Patel RC</searchLink>; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Thomas+CD%22">Thomas CD</searchLink>; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.<br /><searchLink fieldCode="AU" term="%22Rossi+JS%22">Rossi JS</searchLink>; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Franchi+F%22">Franchi F</searchLink>; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA.<br /><searchLink fieldCode="AU" term="%22Keeley+EC%22">Keeley EC</searchLink>; Division of Cardiovascular Medicine, College of Medicine University of Florida Gainesville FL USA.<br /><searchLink fieldCode="AU" term="%22Beitelshees+AL%22">Beitelshees AL</searchLink>; Department of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD USA.<br /><searchLink fieldCode="AU" term="%22Duarte+JD%22">Duarte JD</searchLink>; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.<br /><searchLink fieldCode="AU" term="%22Ortega-Paz+L%22">Ortega-Paz L</searchLink>; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA.<br /><searchLink fieldCode="AU" term="%22Kulick+N%22">Kulick N</searchLink>; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Winget+M%22">Winget M</searchLink>; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+AB%22">Nguyen AB</searchLink>; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Yang+WE%22">Yang WE</searchLink>; Department of Medicine and Program for Personalized and Genomic Medicine University of Maryland School of Medicine Baltimore MD USA.<br /><searchLink fieldCode="AU" term="%22Venkatesh+S%22">Venkatesh S</searchLink>; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Angiolillo+DJ%22">Angiolillo DJ</searchLink>; Division of Cardiology, Department of Medicine, College of Medicine-Jacksonville University of Florida Jacksonville FL USA.<br /><searchLink fieldCode="AU" term="%22Cavallari+LH%22">Cavallari LH</searchLink>; Department of Pharmacotherapy & Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.<br /><searchLink fieldCode="AU" term="%22Lee+CR%22">Lee CR</searchLink>; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USA.<br /><searchLink fieldCode="AU" term="%22Stouffer+GA%22">Stouffer GA</searchLink>; Division of Cardiology and McAllister Heart Institute, School of Medicine University of North Carolina at Chapel Hill Chapel Hill NC USA.
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        Value: 10.1161/JAHA.125.041634
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      – TitleFull: CYP2C19 Phenotype, P2Y12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy.
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