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Apelin facilitates integrin αvβ3 production and enhances metastasis in prostate cancer by activating STAT3 and inhibiting miR-8070.

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Title: Apelin facilitates integrin αvβ3 production and enhances metastasis in prostate cancer by activating STAT3 and inhibiting miR-8070.
Authors: Lin TH; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Urology, Buddhist Tzu Chi General Hospital Taichung Branch, Taichung, Taiwan., Liu SC; Institute of Biomedical Sciences, Mackay Medical College, New Taipei City, Taiwan., Huang YL; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan., Lai CY; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan., He XY; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan., Tsai CH; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan., Fong YC; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan., Wu HC; School of Medicine, China Medical University, Taichung, Taiwan.; Department of Urology, China Medical University Hospital, Taichung, Taiwan.; Department of Urology, China Medical University Beigang Hospital, Beigang, Yunlin, Taiwan., Chang AC; School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan., Lin YY; Translational Medicine Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan., Lin CH; School of Medicine, China Medical University, Taichung, Taiwan.; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan., Tang CH; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan.
Source: International journal of biological sciences [Int J Biol Sci] 2025 Jun 12; Vol. 21 (9), pp. 4117-4128. Date of Electronic Publication: 2025 Jun 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Apelin facilitates integrin αvβ3 production and enhances metastasis in prostate cancer by activating STAT3 and inhibiting miR-8070.
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  Data: <searchLink fieldCode="AU" term="%22Lin+TH%22">Lin TH</searchLink>; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Urology, Buddhist Tzu Chi General Hospital Taichung Branch, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+SC%22">Liu SC</searchLink>; Institute of Biomedical Sciences, Mackay Medical College, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YL%22">Huang YL</searchLink>; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+CY%22">Lai CY</searchLink>; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22He+XY%22">He XY</searchLink>; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+CH%22">Tsai CH</searchLink>; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fong+YC%22">Fong YC</searchLink>; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+HC%22">Wu HC</searchLink>; School of Medicine, China Medical University, Taichung, Taiwan.; Department of Urology, China Medical University Hospital, Taichung, Taiwan.; Department of Urology, China Medical University Beigang Hospital, Beigang, Yunlin, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+AC%22">Chang AC</searchLink>; School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YY%22">Lin YY</searchLink>; Translational Medicine Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; School of Medicine, China Medical University, Taichung, Taiwan.; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tang+CH%22">Tang CH</searchLink>; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.; School of Medicine, China Medical University, Taichung, Taiwan.; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2025 Jun 12; Vol. 21 (9), pp. 4117-4128. <i>Date of Electronic Publication: </i>2025 Jun 12 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International%22">Ivyspring International </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101235568 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1449-2288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214492288%22">14492288 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Sci <i>Subsets: </i>MEDLINE
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              Text: 2025 Jun 12
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