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The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm.

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Title: The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm.
Authors: Wang Z; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Lebedev D; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Li S; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Rao S; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Wu K; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Doyle L; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Wynne K; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Blanco A; Flow Cytometry Core, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland., Mysior MM; Cell Screening Laboratory, School of Biology and Environmental Science, O'Brien Centre for Science, University College Dublin, Dublin, Ireland., Simpson JC; Cell Screening Laboratory, School of Biology and Environmental Science, O'Brien Centre for Science, University College Dublin, Dublin, Ireland., Scholz D; Imaging Core, Conway Institute of Biomolecular and Biomedical Research, University College, Dublin, Ireland., Wülfroth P; F4 Pharma, Vienna, Austria., Zacharowski K; Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany., Kolch W; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland., Eissner G; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Source: Frontiers in immunology [Front Immunol] 2025 Jun 19; Vol. 16, pp. 1591860. Date of Electronic Publication: 2025 Jun 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Lebedev+D%22">Lebedev D</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Rao+S%22">Rao S</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wu+K%22">Wu K</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Doyle+L%22">Doyle L</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wynne+K%22">Wynne K</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Blanco+A%22">Blanco A</searchLink>; Flow Cytometry Core, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Mysior+MM%22">Mysior MM</searchLink>; Cell Screening Laboratory, School of Biology and Environmental Science, O'Brien Centre for Science, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Simpson+JC%22">Simpson JC</searchLink>; Cell Screening Laboratory, School of Biology and Environmental Science, O'Brien Centre for Science, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Scholz+D%22">Scholz D</searchLink>; Imaging Core, Conway Institute of Biomolecular and Biomedical Research, University College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Wülfroth+P%22">Wülfroth P</searchLink>; F4 Pharma, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Zacharowski+K%22">Zacharowski K</searchLink>; Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Kolch+W%22">Kolch W</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Zhernovkov+V%22">Zhernovkov V</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Eissner+G%22">Eissner G</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
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