Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat.
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| Title: | Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat. |
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| Authors: | Vrenken P; National and Kapodistrian University of Athens, Department of Pharmacy, Panepistimiopolis, Zografou, Greece; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany., Vertzoni M; National and Kapodistrian University of Athens, Department of Pharmacy, Panepistimiopolis, Zografou, Greece. Electronic address: vertzoni@pharm.uoa.gr., Frechen S; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany., Solodenko J; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany., Meyer M; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany., Muenster U; Bayer AG, Research and Development, Pharmaceutical Sciences, Advanced Drug Delivery, Wuppertal, Germany., Dallmann A; Bayer HealthCare SAS, Lille, France, on behalf of Bayer AG, Model-Informed Drug Development, Leverkusen, Germany. Electronic address: andre.dallmann@bayer.com. |
| Source: | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 Sep 01; Vol. 212, pp. 107189. Date of Electronic Publication: 2025 Jul 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40615096 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Vrenken+P%22">Vrenken P</searchLink>; National and Kapodistrian University of Athens, Department of Pharmacy, Panepistimiopolis, Zografou, Greece; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Vertzoni+M%22">Vertzoni M</searchLink>; National and Kapodistrian University of Athens, Department of Pharmacy, Panepistimiopolis, Zografou, Greece. Electronic address: vertzoni@pharm.uoa.gr.<br /><searchLink fieldCode="AU" term="%22Frechen+S%22">Frechen S</searchLink>; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Solodenko+J%22">Solodenko J</searchLink>; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+M%22">Meyer M</searchLink>; Bayer AG, Pharmacometrics/Modeling and Simulation, Model-Informed Drug Development, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Muenster+U%22">Muenster U</searchLink>; Bayer AG, Research and Development, Pharmaceutical Sciences, Advanced Drug Delivery, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Dallmann+A%22">Dallmann A</searchLink>; Bayer HealthCare SAS, Lille, France, on behalf of Bayer AG, Model-Informed Drug Development, Leverkusen, Germany. Electronic address: andre.dallmann@bayer.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229317982%22">European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences</searchLink> [Eur J Pharm Sci] 2025 Sep 01; Vol. 212, pp. 107189. <i>Date of Electronic Publication: </i>2025 Jul 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+B%2EV%22">Elsevier Science B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9317982 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0720 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209280987%22">09280987 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharm Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40615096 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejps.2025.107189 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 107189 Titles: – TitleFull: Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Vrenken P – PersonEntity: Name: NameFull: Vertzoni M – PersonEntity: Name: NameFull: Frechen S – PersonEntity: Name: NameFull: Solodenko J – PersonEntity: Name: NameFull: Meyer M – PersonEntity: Name: NameFull: Muenster U – PersonEntity: Name: NameFull: Dallmann A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2025 Sep 01 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1879-0720 Numbering: – Type: volume Value: 212 Titles: – TitleFull: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Type: main |
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