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Sentinel lymph node biopsy without systematic pelvic lymphadenectomy in females with early-stage cervical cancer: final outcome of the SENTIX prospective, single-arm, noninferiority, international trial.

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Title: Sentinel lymph node biopsy without systematic pelvic lymphadenectomy in females with early-stage cervical cancer: final outcome of the SENTIX prospective, single-arm, noninferiority, international trial.
Authors: Cibula D; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic. David.cibula@vfn.cz., Marnitz S; Radiation Oncology Vosspalais, Berlin, Germany., Jarkovský J; Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic., Kocián R; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Dundr P; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Klát J; University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Zapardiel I; Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain., Arencibia O; Unit Gynecology Oncology, Hospital Universitario Materno Infantil de Canarias, Las Palmas, Spain., Landoni F; UNIMIB-IRCCS-San Gerardo Monza, Monza, Italy., Presl J; Department of Gynecology and Obstetrics, University Hospital Pilsen, Charles University Faculty of Medicine in Pilsen, Pilsen, Czech Republic., Raspagliesi F; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Zikán M; Department of Gynecology and Obstetrics, Bulovka University Hospital and Charles University - First Faculty of Medicine, Prague, Czech Republic., van Lonkhuijzen LR; Center for Gynecologic Oncology Amsterdam, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands., Torne A; Gynecologic Oncology Unit, Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain., Sláma J; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Minar L; Department of Gynecology and Obstetrics, University Hospital Brno and Masaryk University, Brno, Czech Republic., Ostojich M; Institute of Oncology Angel H. Roffo, Buenos Aires, Argentina., Pilka R; University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic., Petiz AF; Department of Gynecology, Francisco Gentil Portuguese Oncology Institute, Porto, Portugal., Petzel A; Eviamed, Outpatient Diagnostic & Surgery Center Berlin - Charlottenburg, Berlin, Germany., Burgetová A; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Fischerová D; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Nemejcova K; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Köhler C; Department of Gynecology, Asklepios Clinic Hamburg Altona; Department of Gynecology, DRK Klinik Berlin Westend, Berlin, Germany.
Source: Nature cancer [Nat Cancer] 2025 Sep; Vol. 6 (9), pp. 1585-1594. Date of Electronic Publication: 2025 Jul 04.
Publication Type: Equivalence Trial; Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
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  Data: Sentinel lymph node biopsy without systematic pelvic lymphadenectomy in females with early-stage cervical cancer: final outcome of the SENTIX prospective, single-arm, noninferiority, international trial.
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  Data: <searchLink fieldCode="AU" term="%22Cibula+D%22">Cibula D</searchLink>; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic. David.cibula@vfn.cz.<br /><searchLink fieldCode="AU" term="%22Marnitz+S%22">Marnitz S</searchLink>; Radiation Oncology Vosspalais, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Jarkovský+J%22">Jarkovský J</searchLink>; Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kocián+R%22">Kocián R</searchLink>; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Dundr+P%22">Dundr P</searchLink>; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Klát+J%22">Klát J</searchLink>; University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Zapardiel+I%22">Zapardiel I</searchLink>; Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Arencibia+O%22">Arencibia O</searchLink>; Unit Gynecology Oncology, Hospital Universitario Materno Infantil de Canarias, Las Palmas, Spain.<br /><searchLink fieldCode="AU" term="%22Landoni+F%22">Landoni F</searchLink>; UNIMIB-IRCCS-San Gerardo Monza, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Presl+J%22">Presl J</searchLink>; Department of Gynecology and Obstetrics, University Hospital Pilsen, Charles University Faculty of Medicine in Pilsen, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Raspagliesi+F%22">Raspagliesi F</searchLink>; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zikán+M%22">Zikán M</searchLink>; Department of Gynecology and Obstetrics, Bulovka University Hospital and Charles University - First Faculty of Medicine, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22van+Lonkhuijzen+LR%22">van Lonkhuijzen LR</searchLink>; Center for Gynecologic Oncology Amsterdam, Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Torne+A%22">Torne A</searchLink>; Gynecologic Oncology Unit, Institute Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sláma+J%22">Sláma J</searchLink>; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Minar+L%22">Minar L</searchLink>; Department of Gynecology and Obstetrics, University Hospital Brno and Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Ostojich+M%22">Ostojich M</searchLink>; Institute of Oncology Angel H. Roffo, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Pilka+R%22">Pilka R</searchLink>; University Hospital Olomouc, Palacky University Olomouc, Olomouc, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Petiz+AF%22">Petiz AF</searchLink>; Department of Gynecology, Francisco Gentil Portuguese Oncology Institute, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Petzel+A%22">Petzel A</searchLink>; Eviamed, Outpatient Diagnostic & Surgery Center Berlin - Charlottenburg, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Burgetová+A%22">Burgetová A</searchLink>; Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Fischerová+D%22">Fischerová D</searchLink>; Gynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Nemejcova+K%22">Nemejcova K</searchLink>; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Köhler+C%22">Köhler C</searchLink>; Department of Gynecology, Asklepios Clinic Hamburg Altona; Department of Gynecology, DRK Klinik Berlin Westend, Berlin, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2025 Sep; Vol. 6 (9), pp. 1585-1594. <i>Date of Electronic Publication: </i>2025 Jul 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101761119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-1347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226621347%22">26621347 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cancer <i>Subsets: </i>MEDLINE
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