Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.
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| Title: | Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys. |
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| Authors: | Sawada H; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Kido Y; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Iwasaki M; Department of Biological Material Generation, Shionogi TechnoAdvance Research & Co., Ltd, Japan., Nishida K; Corporate Planning Division, Shionogi TechnoAdvance Research & Co., Ltd, Japan., Mayumi K; Drug Development and Regulatory Science Division, Shionogi & Co., Ltd, Japan., Watari R; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. Electronic address: ryosuke.watari@shionogi.co.jp. |
| Source: | Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2025 Aug; Vol. 63, pp. 101497. Date of Electronic Publication: 2025 Jun 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1880-0920 |
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| DOI: | 10.1016/j.dmpk.2025.101497 |