Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.

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Title: Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.
Authors: Sawada H; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Kido Y; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Iwasaki M; Department of Biological Material Generation, Shionogi TechnoAdvance Research & Co., Ltd, Japan., Nishida K; Corporate Planning Division, Shionogi TechnoAdvance Research & Co., Ltd, Japan., Mayumi K; Drug Development and Regulatory Science Division, Shionogi & Co., Ltd, Japan., Watari R; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. Electronic address: ryosuke.watari@shionogi.co.jp.
Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2025 Aug; Vol. 63, pp. 101497. Date of Electronic Publication: 2025 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.
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  Data: <searchLink fieldCode="AU" term="%22Sawada+H%22">Sawada H</searchLink>; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan.<br /><searchLink fieldCode="AU" term="%22Kido+Y%22">Kido Y</searchLink>; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan.<br /><searchLink fieldCode="AU" term="%22Iwasaki+M%22">Iwasaki M</searchLink>; Department of Biological Material Generation, Shionogi TechnoAdvance Research & Co., Ltd, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+K%22">Nishida K</searchLink>; Corporate Planning Division, Shionogi TechnoAdvance Research & Co., Ltd, Japan.<br /><searchLink fieldCode="AU" term="%22Mayumi+K%22">Mayumi K</searchLink>; Drug Development and Regulatory Science Division, Shionogi & Co., Ltd, Japan.<br /><searchLink fieldCode="AU" term="%22Watari+R%22">Watari R</searchLink>; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. Electronic address: ryosuke.watari@shionogi.co.jp.
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  Data: <searchLink fieldCode="JN" term="%22101164773%22">Drug metabolism and pharmacokinetics</searchLink> [Drug Metab Pharmacokinet] 2025 Aug; Vol. 63, pp. 101497. <i>Date of Electronic Publication: </i>2025 Jun 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101164773 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1880-0920 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213474367%22">13474367 </searchLink><i>NLM ISO Abbreviation: </i>Drug Metab Pharmacokinet <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.dmpk.2025.101497
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      – Code: eng
        Text: English
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        StartPage: 101497
    Titles:
      – TitleFull: Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.
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            NameFull: Sawada H
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            NameFull: Kido Y
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            NameFull: Iwasaki M
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            NameFull: Nishida K
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            NameFull: Mayumi K
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            NameFull: Watari R
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          Dates:
            – D: 01
              M: 08
              Text: 2025 Aug
              Type: published
              Y: 2025
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              Value: 1880-0920
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              Value: 63
          Titles:
            – TitleFull: Drug metabolism and pharmacokinetics
              Type: main
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