Dose-dependent relationship between intra-operative ketamine administration and postoperative delirium: a retrospective cohort study.

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Title: Dose-dependent relationship between intra-operative ketamine administration and postoperative delirium: a retrospective cohort study.
Authors: Kaiser L; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Paschold BS; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Wachtendorf LJ; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Ahrens E; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Tenge T; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Anesthesiology, Medical Faculty, University Hospital Duesseldorf, Heinrich-Heine-University, Duesseldorf, Germany., Redaelli S; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Hentges M; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Sahli SD; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Chen G; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Novack V; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Clinical Research Center, Soroka University Medical Center, Beer-Sheva, Israel., Eikermann M; Department of Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA., Ma H; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA., Schaefer MS; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Center for Anesthesia Research Excellence, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Anesthesiology, Medical Faculty, University Hospital Duesseldorf, Heinrich-Heine-University, Duesseldorf, Germany.
Source: Anaesthesia [Anaesthesia] 2025 Nov; Vol. 80 (11), pp. 1360-1369. Date of Electronic Publication: 2025 Jul 06.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2044 (Electronic) Linking ISSN: 00032409 NLM ISO Abbreviation: Anaesthesia Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1365-2044
DOI:10.1111/anae.16681