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A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns.

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Title: A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns.
Authors: Wissing C; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute for Systems Physiology, Faculty of Medicine, University Clinic, Cologne, Germany., Eschholz LS; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Maheu M; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Section Computational Cognitive Neuroscience, Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sauter K; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Morellini F; Research Group Behavioral Biology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wiegert JS; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Dieter A; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Source: PLoS biology [PLoS Biol] 2025 Jul 07; Vol. 23 (7), pp. e3003228. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns.
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  Data: <searchLink fieldCode="AU" term="%22Wissing+C%22">Wissing C</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute for Systems Physiology, Faculty of Medicine, University Clinic, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Eschholz+LS%22">Eschholz LS</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Maheu+M%22">Maheu M</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Section Computational Cognitive Neuroscience, Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauter+K%22">Sauter K</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Morellini+F%22">Morellini F</searchLink>; Research Group Behavioral Biology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wiegert+JS%22">Wiegert JS</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Dieter+A%22">Dieter A</searchLink>; Synaptic Wiring Lab, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Neurophysiology, MCTN, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2025 Jul 07; Vol. 23 (7), pp. e3003228. <i>Date of Electronic Publication: </i>2025 Jul 07 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101183755 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-7885 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215449173%22">15449173 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Biol <i>Subsets: </i>MEDLINE
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