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Osteoinductive low-dose 3D porous calcium phosphate graphene oxide-integrated matrices enhance osteogenesis and mechanical properties.

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Title: Osteoinductive low-dose 3D porous calcium phosphate graphene oxide-integrated matrices enhance osteogenesis and mechanical properties.
Authors: Hosseini FS; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030., Whitfield T; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030., Orlando JD; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213., Deng C; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213., Abedini AA; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269., Argyrou C; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030., Kan HM; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030., Ghosh D; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030., Maye PF; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030., Lo KW; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Medicine, Division of Endocrinology, School of Medicine, University of Connecticut Health Center, Farmington, CT 06030., Nair L; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Chemical and Bimolecular Engineering, University of Connecticut, Storrs, CT 06269., Sydlik SA; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213., Laurencin CT; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Chemical and Bimolecular Engineering, University of Connecticut, Storrs, CT 06269.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Jul 15; Vol. 122 (28), pp. e2427124122. Date of Electronic Publication: 2025 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hosseini+FS%22">Hosseini FS</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Whitfield+T%22">Whitfield T</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Orlando+JD%22">Orlando JD</searchLink>; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213.<br /><searchLink fieldCode="AU" term="%22Deng+C%22">Deng C</searchLink>; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213.<br /><searchLink fieldCode="AU" term="%22Abedini+AA%22">Abedini AA</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.<br /><searchLink fieldCode="AU" term="%22Argyrou+C%22">Argyrou C</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Kan+HM%22">Kan HM</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Ghosh+D%22">Ghosh D</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Maye+PF%22">Maye PF</searchLink>; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Lo+KW%22">Lo KW</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Medicine, Division of Endocrinology, School of Medicine, University of Connecticut Health Center, Farmington, CT 06030.<br /><searchLink fieldCode="AU" term="%22Nair+L%22">Nair L</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Chemical and Bimolecular Engineering, University of Connecticut, Storrs, CT 06269.<br /><searchLink fieldCode="AU" term="%22Sydlik+SA%22">Sydlik SA</searchLink>; Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA 15213.; Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213.<br /><searchLink fieldCode="AU" term="%22Laurencin+CT%22">Laurencin CT</searchLink>; The Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030.; Department of Orthopaedic Surgery, University of Connecticut Health, Farmington, CT 06030.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.; Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269.; Department of Chemical and Bimolecular Engineering, University of Connecticut, Storrs, CT 06269.
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