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Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life.

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Title: Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life.
Authors: Wu QC; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA., Lee J; Cell Design Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA., Swaminathan A; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Winward A; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Hwang Y; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Socolovsky M; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA., Way JC; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, 201 Brookline Avenue, Boston, MA 02215, USA.; Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA., Klein AM; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.
Source: Protein engineering, design & selection : PEDS [Protein Eng Des Sel] 2025 Jan 10; Vol. 38.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101186484 Publication Model: Print Cited Medium: Internet ISSN: 1741-0134 (Electronic) Linking ISSN: 17410126 NLM ISO Abbreviation: Protein Eng Des Sel Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wu+QC%22">Wu QC</searchLink>; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Cell Design Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA.<br /><searchLink fieldCode="AU" term="%22Swaminathan+A%22">Swaminathan A</searchLink>; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Winward+A%22">Winward A</searchLink>; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+Y%22">Hwang Y</searchLink>; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Socolovsky+M%22">Socolovsky M</searchLink>; Department of Molecular, Cell and Cancer Biology, UMASS Chan Medical School, 364 Plantation St, Worcester, MA 01605, USA.<br /><searchLink fieldCode="AU" term="%22Way+JC%22">Way JC</searchLink>; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, 201 Brookline Avenue, Boston, MA 02215, USA.; Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Klein+AM%22">Klein AM</searchLink>; Department of Systems Biology, Harvard Medical School, 210 Longwood Avenue, Boston, MA 02115, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101186484 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1741-0134 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217410126%22">17410126 </searchLink><i>NLM ISO Abbreviation: </i>Protein Eng Des Sel <i>Subsets: </i>MEDLINE
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        Value: 10.1093/protein/gzaf009
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        Text: English
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      – TitleFull: Linker minimization and characterization of Fc-fused interleukin-17A for increased in vivo half-life.
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            – D: 10
              M: 01
              Text: 2025 Jan 10
              Type: published
              Y: 2025
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