Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples.
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| Title: | Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples. |
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| Authors: | Ju CW; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA., Lyu R; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Li H; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Wei J; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Parra Vitela AJ; Colon and Rectal Surgery, Advocate Lutheran General Hospital, Park Ridge, IL, USA., Dougherty U; Department of Medicine, The University of Chicago, Chicago, IL, USA., Kwesi A; Department of Medicine, The University of Chicago, Chicago, IL, USA., Luna A; Department of Medicine, The University of Chicago, Chicago, IL, USA., Zhu X; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Shen S; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; Department of Chemistry, The Hong Kong University of Science and Technology, Hong Kong, China., Liu Y; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Wang L; The Laboratory of Microbiome and Microecological Technology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Cui X; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Xu Y; Department of Chemistry, New York University, New York, NY, USA., Jiang B; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Ji Y; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Xia P; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., West-Szymanski DC; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Sun C; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Zhong Y; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Ye C; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Moran A; Department of Pathology, The University of Chicago, Chicago, IL, USA., Lehmann C; Department of Medicine, The University of Chicago, Chicago, IL, USA., Pamer E; Department of Medicine, The University of Chicago, Chicago, IL, USA., Zhang W; Department of Preventive Medicine and The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Bissonnette M; Department of Medicine, The University of Chicago, Chicago, IL, USA. mbissonn@bsd.uchicago.edu., Zhang LS; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China. zhangls@ust.hk.; Department of Chemistry, The Hong Kong University of Science and Technology, Hong Kong, China. zhangls@ust.hk., He C; Department of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu. |
| Source: | Nature biotechnology [Nat Biotechnol] 2026 May; Vol. 44 (5), pp. 752-758. Date of Electronic Publication: 2025 Jul 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40629040 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ju+CW%22">Ju CW</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lyu+R%22">Lyu R</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Wei+J%22">Wei J</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Parra+Vitela+AJ%22">Parra Vitela AJ</searchLink>; Colon and Rectal Surgery, Advocate Lutheran General Hospital, Park Ridge, IL, USA.<br /><searchLink fieldCode="AU" term="%22Dougherty+U%22">Dougherty U</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kwesi+A%22">Kwesi A</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Luna+A%22">Luna A</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shen+S%22">Shen S</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; Department of Chemistry, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; The Laboratory of Microbiome and Microecological Technology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Cui+X%22">Cui X</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Chemistry, New York University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+B%22">Jiang B</searchLink>; 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Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Ye+C%22">Ye C</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Moran+A%22">Moran A</searchLink>; Department of Pathology, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lehmann+C%22">Lehmann C</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Pamer+E%22">Pamer E</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Preventive Medicine and The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bissonnette+M%22">Bissonnette M</searchLink>; Department of Medicine, The University of Chicago, Chicago, IL, USA. mbissonn@bsd.uchicago.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+LS%22">Zhang LS</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China. zhangls@ust.hk.; Department of Chemistry, The Hong Kong University of Science and Technology, Hong Kong, China. zhangls@ust.hk.<br /><searchLink fieldCode="AU" term="%22He+C%22">He C</searchLink>; Department of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229604648%22">Nature biotechnology</searchLink> [Nat Biotechnol] 2026 May; Vol. 44 (5), pp. 752-758. <i>Date of Electronic Publication: </i>2025 Jul 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+America+Publishing%22">Nature America Publishing </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9604648 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1696 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210870156%22">10870156 </searchLink><i>NLM ISO Abbreviation: </i>Nat Biotechnol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40629040 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41587-025-02731-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 752 Titles: – TitleFull: Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ju CW – PersonEntity: Name: NameFull: Lyu R – PersonEntity: Name: NameFull: Li H – PersonEntity: Name: NameFull: Wei J – PersonEntity: Name: NameFull: Parra Vitela AJ – PersonEntity: Name: NameFull: Dougherty U – PersonEntity: Name: NameFull: Kwesi A – PersonEntity: Name: NameFull: Luna A – PersonEntity: Name: NameFull: Zhu X – PersonEntity: Name: NameFull: Shen S – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Wang L – PersonEntity: Name: NameFull: Cui X – PersonEntity: Name: NameFull: Xu Y – PersonEntity: Name: NameFull: Jiang B – PersonEntity: Name: NameFull: Ji Y – PersonEntity: Name: NameFull: Xia P – PersonEntity: Name: NameFull: West-Szymanski DC – PersonEntity: Name: NameFull: Sun C – PersonEntity: Name: NameFull: Zhong Y – PersonEntity: Name: NameFull: Ye C – PersonEntity: Name: NameFull: Moran A – PersonEntity: Name: NameFull: Lehmann C – PersonEntity: Name: NameFull: Pamer E – PersonEntity: Name: NameFull: Zhang W – PersonEntity: Name: NameFull: Bissonnette M – PersonEntity: Name: NameFull: Zhang LS – PersonEntity: Name: NameFull: He C IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2026 May Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1546-1696 Numbering: – Type: volume Value: 44 – Type: issue Value: 5 Titles: – TitleFull: Nature biotechnology Type: main |
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