Fusion of Complement Fragment C3d Enhances Germinal Center Responses to HIV-1 Envelope Glycoproteins.

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Title: Fusion of Complement Fragment C3d Enhances Germinal Center Responses to HIV-1 Envelope Glycoproteins.
Authors: de Gast M; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Hernández-Pérez S; Institute of Immunity and Transplantation, University College London, London, UK., Pradhan A; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA., Kruijer S; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Olijhoek W; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Baken IJL; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Matti C; Institute of Immunity and Transplantation, University College London, London, UK., Breeuwsma M; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Tean ZS; Institute of Immunity and Transplantation, University College London, London, UK., van Keizerswaard WJC; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Zoomer S; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Burger JA; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Caniels TG; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Sliepen K; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Derking R; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Thapa M; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA., Grakoui A; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA., Heesters BA; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Claireaux M; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands., Sanders RW; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA., Tolar P; Institute of Immunity and Transplantation, University College London, London, UK., Kasturi SP; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA., van Gils MJ; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 01. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22de+Gast+M%22">de Gast M</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hernández-Pérez+S%22">Hernández-Pérez S</searchLink>; Institute of Immunity and Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pradhan+A%22">Pradhan A</searchLink>; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kruijer+S%22">Kruijer S</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Olijhoek+W%22">Olijhoek W</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Baken+IJL%22">Baken IJL</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Matti+C%22">Matti C</searchLink>; Institute of Immunity and Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Breeuwsma+M%22">Breeuwsma M</searchLink>; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Tean+ZS%22">Tean ZS</searchLink>; Institute of Immunity and Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Keizerswaard+WJC%22">van Keizerswaard WJC</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zoomer+S%22">Zoomer S</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+JA%22">Burger JA</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Caniels+TG%22">Caniels TG</searchLink>; Dept. 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Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thapa+M%22">Thapa M</searchLink>; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Grakoui+A%22">Grakoui A</searchLink>; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Heesters+BA%22">Heesters BA</searchLink>; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Claireaux+M%22">Claireaux M</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sanders+RW%22">Sanders RW</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tolar+P%22">Tolar P</searchLink>; Institute of Immunity and Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kasturi+SP%22">Kasturi SP</searchLink>; Emory National Primate Research Center, Department of Pathology and Laboratory Medicine, Emory School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Dept. Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands.
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