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Immunobiological effects of tocilizumab across respiratory subphenotypes in COVID-19 ARDS.

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Title: Immunobiological effects of tocilizumab across respiratory subphenotypes in COVID-19 ARDS.
Authors: Rademaker E; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. e.rademaker-2@umcutrecht.nl.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands. e.rademaker-2@umcutrecht.nl., Filippini DFL; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Haitsma Mulier JLG; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands., Slim MA; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., van Amstel RBE; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Bhavani SV; Department of Medicine, Emory University, Atlanta, Georgia., Juffermans NP; Laboratory of Translational Intensive Care, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands., de Grooth HS; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Derde LPG; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands., Cremer OL; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands., Bos LDJ; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Pulmonology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Laboratory of Experimental Intensive Care and Anaesthesiology (L.E.I.C.A.), University of Amsterdam, Amsterdam, The Netherlands.
Corporate Authors: Amsterdam U. M. C. COVID-19 Biobank Study Group
Source: Intensive care medicine experimental [Intensive Care Med Exp] 2025 Jul 09; Vol. 13 (1), pp. 70. Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag, GmbH Country of Publication: Germany NLM ID: 101645149 Publication Model: Electronic Cited Medium: Print ISSN: 2197-425X (Print) Linking ISSN: 2197425X NLM ISO Abbreviation: Intensive Care Med Exp Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Immunobiological effects of tocilizumab across respiratory subphenotypes in COVID-19 ARDS.
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  Data: <searchLink fieldCode="AU" term="%22Rademaker+E%22">Rademaker E</searchLink>; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. e.rademaker-2@umcutrecht.nl.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands. e.rademaker-2@umcutrecht.nl.<br /><searchLink fieldCode="AU" term="%22Filippini+DFL%22">Filippini DFL</searchLink>; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Haitsma+Mulier+JLG%22">Haitsma Mulier JLG</searchLink>; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Slim+MA%22">Slim MA</searchLink>; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Amstel+RBE%22">van Amstel RBE</searchLink>; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bhavani+SV%22">Bhavani SV</searchLink>; Department of Medicine, Emory University, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Juffermans+NP%22">Juffermans NP</searchLink>; Laboratory of Translational Intensive Care, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.; Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Grooth+HS%22">de Grooth HS</searchLink>; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Derde+LPG%22">Derde LPG</searchLink>; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cremer+OL%22">Cremer OL</searchLink>; Department of Intensive Care Medicine, UMC Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bos+LDJ%22">Bos LDJ</searchLink>; Department of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Pulmonology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Laboratory of Experimental Intensive Care and Anaesthesiology (L.E.I.C.A.), University of Amsterdam, Amsterdam, The Netherlands.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%2C+GmbH%22">Springer-Verlag, GmbH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101645149 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2197-425X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222197425X%22">2197425X </searchLink><i>NLM ISO Abbreviation: </i>Intensive Care Med Exp <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Jul 09
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