Selective remodelling of the adipose niche in obesity and weight loss.

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Title: Selective remodelling of the adipose niche in obesity and weight loss.
Authors: Miranda AMA; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., McAllan L; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Mazzei G; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Andrew I; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Davies I; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Ertugrul M; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Kenkre J; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Kudo H; Section for Pathology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Carrelha J; Department of Immunology and Inflammation, Imperial College London, London, UK., Patel B; MRC Laboratory of Medical Sciences, London, UK.; Department of Biochemistry, Oxford University, Oxford, UK., Newton S; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK., Pollard A; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Cross A; Translational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., McCallion O; Translational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Jang M; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Choi KL; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Brown S; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Rasool Y; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Adamo M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK., Elkalaawy M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK., Jenkinson A; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK., Mohammadi B; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK., Hashemi M; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK., Goldin R; Imperial College Healthcare NHS Trust, London, UK.; Section for Pathology, Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Game L; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK., Hester J; Translational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Issa F; Translational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Ryan DG; MRC Mitochondrial Biology Unit, Keith Peter's building, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Ortega P; Imperial College Healthcare NHS Trust, London, UK., Ahmed AR; Imperial College Healthcare NHS Trust, London, UK.; Department of Surgery and Cancer, Imperial College London, London, UK., Batterham RL; UCLH Bariatric Centre for Weight Loss, Weight Management and Metabolic and Endocrine Surgery, University College London Hospitals, London, UK.; Centre for Obesity Research, Rayne Institute, Department of Medicine, University College London, London, UK.; National Institute of Health Research, University College London Hospitals Biomedical Research Centre, London, UK., Chambers JC; Imperial College Healthcare NHS Trust, London, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kooner JS; Imperial College Healthcare NHS Trust, London, UK.; Department of Cardiology, Ealing Hospital, London North West University Healthcare NHS Trust, Middlesex, UK.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Baranasic D; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; MRC Laboratory of Medical Sciences, London, UK.; Division of Electronics, Ruđer Bošković Institute, Zagreb, Croatia., Noseda M; National Heart and Lung Institute, Imperial College London, London, UK., Tan T; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Scott WR; Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. w.scott@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. w.scott@imperial.ac.uk.; Imperial College Healthcare NHS Trust, London, UK. w.scott@imperial.ac.uk.
Source: Nature [Nature] 2025 Aug; Vol. 644 (8077), pp. 769-779. Date of Electronic Publication: 2025 Jul 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. w.scott@imperial.ac.uk.; MRC Laboratory of Medical Sciences, London, UK. w.scott@imperial.ac.uk.; Imperial College Healthcare NHS Trust, London, UK. w.scott@imperial.ac.uk.
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