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How changes in post-traumatic stress disorder (PTSD) severity mediate substance use disorder (SUD) severity during and after treatment for co-occurring PTSD and SUD: Results from Project Harmony.

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Title: How changes in post-traumatic stress disorder (PTSD) severity mediate substance use disorder (SUD) severity during and after treatment for co-occurring PTSD and SUD: Results from Project Harmony.
Authors: Hien DA; Center of Alcohol and Substance Use Studies, Rutgers University-New Brunswick, Piscataway, NJ, USA., Gette JA; Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, KS, USA., Blakey SM; RTI International, Research Triangle Park, North Carolina, USA., Piccirillo ML; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA., Back SE; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.; Ralph H. Johnson VA Healthcare System, Charleston, SC, USA., Bauer AG; Center of Alcohol and Substance Use Studies, Rutgers University-New Brunswick, Piscataway, NJ, USA., Ebrahimi CT; Department of Psychology, The New School, New York, NY, USA., Ellis RA; Department of Psychiatry, Harvard Medical School and McLean Hospital, Boston, MA, USA., Killeen TK; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA., Lehinger EA; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA., López-Castro T; Department of Psychology, City College of New York, New York, NY, USA., Norman SB; Department of Psychiatry, University of California, San Diego and San Diego VA, San Diego, CA, USA.; National Center for PTSD, White River Junction, Hatford, VT, USA., Ruglass LM; Center of Alcohol and Substance Use Studies, Rutgers University-New Brunswick, Piscataway, NJ, USA.; Department of Psychology, City College of New York, New York, NY, USA., Saraiya TC; Center of Alcohol and Substance Use Studies, Rutgers University-New Brunswick, Piscataway, NJ, USA.; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA., Saavedra LM; RTI International, Research Triangle Park, North Carolina, USA., Morgan-López AA; RTI International, Research Triangle Park, North Carolina, USA.
Source: Addiction (Abingdon, England) [Addiction] 2025 Nov; Vol. 120 (11), pp. 2245-2257. Date of Electronic Publication: 2025 Jul 10.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9304118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1360-0443 (Electronic) Linking ISSN: 09652140 NLM ISO Abbreviation: Addiction Subsets: MEDLINE
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