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Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation.

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Title: Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation.
Authors: Dürholz K; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Ehnes L; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Linnerbauer M; Deutsches Zentrum Immuntherapie (DZI), and.; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schmid E; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Danzer H; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Hinzpeter-Schmidt M; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Lößlein L; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Amend L; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany., Frech M; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Azizov V; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Schälter F; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Gessner A; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany., Lucas S; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Lesker TR; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany., Taudte RV; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.; Core Facility for Metabolomics, Philipp University Marburg, Marburg, Germany., Hofmann J; Department of Biology, Division of Biochemistry, Friedrich-Alexander University, Erlangen, Germany., Beyer F; Institute of Biochemistry, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany., Bootz-Maoz H; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel., Reich Y; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel., Romano H; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel., Mauro D; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Beckervordersandforth R; Institute of Biochemistry, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany., Kragsnaes MS; Department of Rheumatology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Ellingsen T; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Xiang W; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany., Haghikia A; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Akdis CA; Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland., Ciccia F; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy., Bäuerle T; Radiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Sarter K; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Strowig T; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany., Yissachar N; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel., Schett G; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and., Rothhammer V; Deutsches Zentrum Immuntherapie (DZI), and.; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Zaiss MM; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jul 10; Vol. 135 (18). Date of Electronic Publication: 2025 Jul 10 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Dürholz+K%22">Dürholz K</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Ehnes+L%22">Ehnes L</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Linnerbauer+M%22">Linnerbauer M</searchLink>; Deutsches Zentrum Immuntherapie (DZI), and.; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+E%22">Schmid E</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Danzer+H%22">Danzer H</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Hinzpeter-Schmidt+M%22">Hinzpeter-Schmidt M</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Lößlein+L%22">Lößlein L</searchLink>; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Amend+L%22">Amend L</searchLink>; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Frech+M%22">Frech M</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Azizov+V%22">Azizov V</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Schälter+F%22">Schälter F</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; 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Department of Biology, Division of Biochemistry, Friedrich-Alexander University, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Beyer+F%22">Beyer F</searchLink>; Institute of Biochemistry, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Bootz-Maoz+H%22">Bootz-Maoz H</searchLink>; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Reich+Y%22">Reich Y</searchLink>; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Romano+H%22">Romano H</searchLink>; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Mauro+D%22">Mauro D</searchLink>; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Beckervordersandforth+R%22">Beckervordersandforth R</searchLink>; Institute of Biochemistry, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Kragsnaes+MS%22">Kragsnaes MS</searchLink>; Department of Rheumatology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Ellingsen+T%22">Ellingsen T</searchLink>; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Xiang+W%22">Xiang W</searchLink>; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.<br /><searchLink fieldCode="AU" term="%22Haghikia+A%22">Haghikia A</searchLink>; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Akdis+CA%22">Akdis CA</searchLink>; Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ciccia+F%22">Ciccia F</searchLink>; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli,' Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bäuerle+T%22">Bäuerle T</searchLink>; Radiologisches Institut, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Sarter+K%22">Sarter K</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Strowig+T%22">Strowig T</searchLink>; Department of Microbial Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany; Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Yissachar+N%22">Yissachar N</searchLink>; The Goodman Faculty of Life Sciences, and Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Schett+G%22">Schett G</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.<br /><searchLink fieldCode="AU" term="%22Rothhammer+V%22">Rothhammer V</searchLink>; Deutsches Zentrum Immuntherapie (DZI), and.; Department of Neurology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Zaiss+MM%22">Zaiss MM</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology.; Deutsches Zentrum Immuntherapie (DZI), and.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Jul 10; Vol. 135 (18). <i>Date of Electronic Publication: </i>2025 Jul 10 (<i>Print Publication: </i>2025).
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