View in EDS

Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors.

Saved in:
Bibliographic Details
Title: Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors.
Authors: Nelson BE; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Janku F; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Fu S; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Dumbrava EE; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Hong DS; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Karp DD; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Naing A; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Rodon J; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Tsimberidou AM; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas., Murthy R; Department of Interventional Radiology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Sheth RA; Department of Interventional Radiology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Amaria RN; Department of Melanoma Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Conley AP; Department of Sarcoma Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Damodaran S; Department of Breast Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Raghav KPS; Department of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas., Carapanceanu N; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Singh MP; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Carapanceanu V; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Pezeshki A; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Leontovich AA; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Kreider BL; Biomed Valley Discoveries, Kansas City, Missouri., Tung D; Biomed Valley Discoveries, Kansas City, Missouri., Varterasian M; Biomed Valley Discoveries, Kansas City, Missouri., Khazaie K; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Piha-Paul SA; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Sep 15; Vol. 31 (18), pp. 3864-3875.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40643985
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Nelson+BE%22">Nelson BE</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Janku+F%22">Janku F</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Fu+S%22">Fu S</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Dumbrava+EE%22">Dumbrava EE</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Hong+DS%22">Hong DS</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Karp+DD%22">Karp DD</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Naing+A%22">Naing A</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Rodon+J%22">Rodon J</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Tsimberidou+AM%22">Tsimberidou AM</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Murthy+R%22">Murthy R</searchLink>; Department of Interventional Radiology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sheth+RA%22">Sheth RA</searchLink>; Department of Interventional Radiology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Amaria+RN%22">Amaria RN</searchLink>; Department of Melanoma Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Conley+AP%22">Conley AP</searchLink>; Department of Sarcoma Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Damodaran+S%22">Damodaran S</searchLink>; Department of Breast Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Raghav+KPS%22">Raghav KPS</searchLink>; Department of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Carapanceanu+N%22">Carapanceanu N</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Singh+MP%22">Singh MP</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Carapanceanu+V%22">Carapanceanu V</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Pezeshki+A%22">Pezeshki A</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Leontovich+AA%22">Leontovich AA</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Kreider+BL%22">Kreider BL</searchLink>; Biomed Valley Discoveries, Kansas City, Missouri.<br /><searchLink fieldCode="AU" term="%22Tung+D%22">Tung D</searchLink>; Biomed Valley Discoveries, Kansas City, Missouri.<br /><searchLink fieldCode="AU" term="%22Varterasian+M%22">Varterasian M</searchLink>; Biomed Valley Discoveries, Kansas City, Missouri.<br /><searchLink fieldCode="AU" term="%22Khazaie+K%22">Khazaie K</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Piha-Paul+SA%22">Piha-Paul SA</searchLink>; Department of Investigational Cancer Therapeutics, U.T. M.D. Anderson Cancer Center, Houston, Texas.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Sep 15; Vol. 31 (18), pp. 3864-3875.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase I
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40643985
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1158/1078-0432.CCR-24-3952
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3864
    Titles:
      – TitleFull: Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Nelson BE
      – PersonEntity:
          Name:
            NameFull: Janku F
      – PersonEntity:
          Name:
            NameFull: Fu S
      – PersonEntity:
          Name:
            NameFull: Dumbrava EE
      – PersonEntity:
          Name:
            NameFull: Hong DS
      – PersonEntity:
          Name:
            NameFull: Karp DD
      – PersonEntity:
          Name:
            NameFull: Naing A
      – PersonEntity:
          Name:
            NameFull: Rodon J
      – PersonEntity:
          Name:
            NameFull: Tsimberidou AM
      – PersonEntity:
          Name:
            NameFull: Murthy R
      – PersonEntity:
          Name:
            NameFull: Sheth RA
      – PersonEntity:
          Name:
            NameFull: Amaria RN
      – PersonEntity:
          Name:
            NameFull: Conley AP
      – PersonEntity:
          Name:
            NameFull: Damodaran S
      – PersonEntity:
          Name:
            NameFull: Raghav KPS
      – PersonEntity:
          Name:
            NameFull: Carapanceanu N
      – PersonEntity:
          Name:
            NameFull: Singh MP
      – PersonEntity:
          Name:
            NameFull: Carapanceanu V
      – PersonEntity:
          Name:
            NameFull: Pezeshki A
      – PersonEntity:
          Name:
            NameFull: Leontovich AA
      – PersonEntity:
          Name:
            NameFull: Kreider BL
      – PersonEntity:
          Name:
            NameFull: Tung D
      – PersonEntity:
          Name:
            NameFull: Varterasian M
      – PersonEntity:
          Name:
            NameFull: Khazaie K
      – PersonEntity:
          Name:
            NameFull: Piha-Paul SA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 09
              Text: 2025 Sep 15
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1557-3265
          Numbering:
            – Type: volume
              Value: 31
            – Type: issue
              Value: 18
          Titles:
            – TitleFull: Clinical cancer research : an official journal of the American Association for Cancer Research
              Type: main
ResultId 1