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Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys.

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Title: Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys.
Authors: Pitts J; Gilead Sciences, Inc., Foster City, CA, USA., Zamora JLR; Gilead Sciences, Inc., Foster City, CA, USA., Manhas S; Gilead Sciences, Inc., Foster City, CA, USA., Aeschbacher T; Gilead Sciences, Inc., Foster City, CA, USA., Chan J; Gilead Sciences, Inc., Foster City, CA, USA., Cutillas V; Gilead Sciences, Inc., Foster City, CA, USA., Nair V; Gilead Sciences, Inc., Foster City, CA, USA., Riola NC; Gilead Sciences, Inc., Foster City, CA, USA., Vijjapurapu A; Gilead Sciences, Inc., Foster City, CA, USA., Vermillion MS; Lovelace Biomedical Research Institute, Albuquerque, NM, USA., Eng S; Gilead Sciences, Inc., Foster City, CA, USA., Richards C; Gilead Sciences, Inc., Foster City, CA, USA., Han D; Gilead Sciences, Inc., Foster City, CA, USA., Perry JK; Gilead Sciences, Inc., Foster City, CA, USA., Chaudhuri S; Gilead Sciences, Inc., Foster City, CA, USA., Liu SW; Gilead Sciences, Inc., Foster City, CA, USA., Martinez C; Gilead Sciences, Inc., Foster City, CA, USA., Peinovich N; Gilead Sciences, Inc., Foster City, CA, USA., Sun KH; Gilead Sciences, Inc., Foster City, CA, USA., Cai A; Gilead Sciences, Inc., Foster City, CA, USA., Martin R; Gilead Sciences, Inc., Foster City, CA, USA., Moshiri J; Gilead Sciences, Inc., Foster City, CA, USA., Hedskog C; Gilead Sciences, Inc., Foster City, CA, USA., Babusis D; Gilead Sciences, Inc., Foster City, CA, USA., Siegel DS; Gilead Sciences, Inc., Foster City, CA, USA., Kalla R; Gilead Sciences, Inc., Foster City, CA, USA., Avadhanula V; Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Piedra PA; Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Stobbelaar K; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, BE, Belgium.; Respiratory Virus Repository (ReViRAnt), University of Antwerp, Antwerp, BE, Belgium., Delputte PL; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, BE, Belgium.; Respiratory Virus Repository (ReViRAnt), University of Antwerp, Antwerp, BE, Belgium., Marceau C; Gilead Sciences, Inc., Foster City, CA, USA., Mateo R; Gilead Sciences, Inc., Foster City, CA, USA., Maiorova E; Gilead Sciences, Inc., Foster City, CA, USA., Mo H; Gilead Sciences, Inc., Foster City, CA, USA., Subramanian R; Gilead Sciences, Inc., Foster City, CA, USA., Mackman RL; Gilead Sciences, Inc., Foster City, CA, USA., Cihlar T; Gilead Sciences, Inc., Foster City, CA, USA., Fletcher SP; Gilead Sciences, Inc., Foster City, CA, USA., Bilello JP; Gilead Sciences, Inc., Foster City, CA, USA. john.bilello@gilead.com.
Source: Nature communications [Nat Commun] 2025 Jul 11; Vol. 16 (1), pp. 6437. Date of Electronic Publication: 2025 Jul 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-61595-3