View in EDS

A genome-wide association study identifies an African-specific locus on chromosome 21q22.12 associated with Burkitt lymphoma risk and survival.

Saved in:
Bibliographic Details
Title: A genome-wide association study identifies an African-specific locus on chromosome 21q22.12 associated with Burkitt lymphoma risk and survival.
Authors: Dutta D; Integrative Tumor Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Gouveia MH; Center for Research on Genomics & Global Health, Division of Intramural Research, National Human Genome Research Institute, Bethesda, MD, USA., Gorman BR; Trans-Divisional Research Program, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Adu-Gyamfi A; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Lee CH; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Ogwang MD; Department of Surgery, St. Mary's Hospital, Lacor, Gulu, Uganda., Kerchan P; Medical Superintendent's Office, Kuluva Hospital, Arua, Uganda., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Tenge CN; Department of Pediatrics, Moi University, Eldoret, Kenya., Were PA; EMBLEM Study, Academic Model Providing Access To Healthcare (AMPATH), Moi Teaching and Referral Hospital, Eldoret, Kenya., Wekesa WN; Department of Pathology, Moi University, Eldoret, Kenya., Tenge RK; Department of Surgery, Moi University, Eldoret, Kenya., Masalu N; Department of Oncology, Bugando Medical Center, Mwanza, Tanzania., Kawira EL; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Kinyera T; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda., Otim I; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda., Nabalende H; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda., Dhudha H; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Candia B; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda., Abaru J; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda., Yan W; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Florez-Vargas O; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Xie Y; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Ho M; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Ayers LW; Department of Pathology, Ohio State University, Columbus, OH, USA., Bhatia K; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Goedert JJ; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Pfeiffer RM; Biostatistics Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Manning M; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Hutchinson A; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Cole N; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Luo W; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Hicks B; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Chagaluka G; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Johnston WT; Department of Health Sciences, Epidemiology and Cancer Statistics Group, University of York, York, UK., Mutalima N; Cancer Epidemiology Unit, University of Oxford, Oxford, UK., Borgstein E; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Liomba GN; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Kamiza S; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Mkandawire N; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Molyneux EM; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi., Mitambo C; Research Department, National Health Sciences Research Committee, Ministry of Health, Lilongwe, Malawi., Newton R; Department of Health Sciences, Epidemiology and Cancer Statistics Group, University of York, York, UK., Siebert R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.; German Center for Child and Adolescent Health (DZKJ), Ulm, Germany., Dean M; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Yeager M; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA., Chanock SJ; Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA., Prokunina-Olsson L; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA., Mbulaiteye SM; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA. mbulaits@mail.nih.gov.
Source: Leukemia [Leukemia] 2025 Sep; Vol. 39 (9), pp. 2196-2206. Date of Electronic Publication: 2025 Jul 11.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40646133
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A genome-wide association study identifies an African-specific locus on chromosome 21q22.12 associated with Burkitt lymphoma risk and survival.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dutta+D%22">Dutta D</searchLink>; Integrative Tumor Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gouveia+MH%22">Gouveia MH</searchLink>; Center for Research on Genomics & Global Health, Division of Intramural Research, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gorman+BR%22">Gorman BR</searchLink>; Trans-Divisional Research Program, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Adu-Gyamfi+A%22">Adu-Gyamfi A</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ogwang+MD%22">Ogwang MD</searchLink>; Department of Surgery, St. Mary's Hospital, Lacor, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Kerchan+P%22">Kerchan P</searchLink>; Medical Superintendent's Office, Kuluva Hospital, Arua, Uganda.<br /><searchLink fieldCode="AU" term="%22Reynolds+SJ%22">Reynolds SJ</searchLink>; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tenge+CN%22">Tenge CN</searchLink>; Department of Pediatrics, Moi University, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Were+PA%22">Were PA</searchLink>; EMBLEM Study, Academic Model Providing Access To Healthcare (AMPATH), Moi Teaching and Referral Hospital, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Wekesa+WN%22">Wekesa WN</searchLink>; Department of Pathology, Moi University, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Tenge+RK%22">Tenge RK</searchLink>; Department of Surgery, Moi University, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Masalu+N%22">Masalu N</searchLink>; Department of Oncology, Bugando Medical Center, Mwanza, Tanzania.<br /><searchLink fieldCode="AU" term="%22Kawira+EL%22">Kawira EL</searchLink>; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania.<br /><searchLink fieldCode="AU" term="%22Kinyera+T%22">Kinyera T</searchLink>; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Otim+I%22">Otim I</searchLink>; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Nabalende+H%22">Nabalende H</searchLink>; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Dhudha+H%22">Dhudha H</searchLink>; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania.<br /><searchLink fieldCode="AU" term="%22Candia+B%22">Candia B</searchLink>; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Abaru+J%22">Abaru J</searchLink>; EMBLEM Study, African Field Epidemiology Network, Gulu, Uganda.<br /><searchLink fieldCode="AU" term="%22Yan+W%22">Yan W</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Florez-Vargas+O%22">Florez-Vargas O</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ho+M%22">Ho M</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ayers+LW%22">Ayers LW</searchLink>; Department of Pathology, Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Bhatia+K%22">Bhatia K</searchLink>; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Goedert+JJ%22">Goedert JJ</searchLink>; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pfeiffer+RM%22">Pfeiffer RM</searchLink>; Biostatistics Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Manning+M%22">Manning M</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hutchinson+A%22">Hutchinson A</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cole+N%22">Cole N</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Luo+W%22">Luo W</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+B%22">Hicks B</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chagaluka+G%22">Chagaluka G</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Johnston+WT%22">Johnston WT</searchLink>; Department of Health Sciences, Epidemiology and Cancer Statistics Group, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Mutalima+N%22">Mutalima N</searchLink>; Cancer Epidemiology Unit, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Borgstein+E%22">Borgstein E</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Liomba+GN%22">Liomba GN</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Kamiza+S%22">Kamiza S</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Mkandawire+N%22">Mkandawire N</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Molyneux+EM%22">Molyneux EM</searchLink>; Departments of Pediatrics and Surgery, University of Malawi, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Mitambo+C%22">Mitambo C</searchLink>; Research Department, National Health Sciences Research Committee, Ministry of Health, Lilongwe, Malawi.<br /><searchLink fieldCode="AU" term="%22Newton+R%22">Newton R</searchLink>; Department of Health Sciences, Epidemiology and Cancer Statistics Group, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Siebert+R%22">Siebert R</searchLink>; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.; German Center for Child and Adolescent Health (DZKJ), Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Dean+M%22">Dean M</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yeager+M%22">Yeager M</searchLink>; Division of Cancer Epidemiology & Genetics, Cancer Genomics Research Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chanock+SJ%22">Chanock SJ</searchLink>; Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Prokunina-Olsson+L%22">Prokunina-Olsson L</searchLink>; Division of Cancer Epidemiology & Genetics, Laboratory of Translational Genomics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mbulaiteye+SM%22">Mbulaiteye SM</searchLink>; Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, MD, USA. mbulaits@mail.nih.gov.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2025 Sep; Vol. 39 (9), pp. 2196-2206. <i>Date of Electronic Publication: </i>2025 Jul 11.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Intramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40646133
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41375-025-02690-8
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2196
    Titles:
      – TitleFull: A genome-wide association study identifies an African-specific locus on chromosome 21q22.12 associated with Burkitt lymphoma risk and survival.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dutta D
      – PersonEntity:
          Name:
            NameFull: Gouveia MH
      – PersonEntity:
          Name:
            NameFull: Gorman BR
      – PersonEntity:
          Name:
            NameFull: Adu-Gyamfi A
      – PersonEntity:
          Name:
            NameFull: Lee CH
      – PersonEntity:
          Name:
            NameFull: Ogwang MD
      – PersonEntity:
          Name:
            NameFull: Kerchan P
      – PersonEntity:
          Name:
            NameFull: Reynolds SJ
      – PersonEntity:
          Name:
            NameFull: Tenge CN
      – PersonEntity:
          Name:
            NameFull: Were PA
      – PersonEntity:
          Name:
            NameFull: Wekesa WN
      – PersonEntity:
          Name:
            NameFull: Tenge RK
      – PersonEntity:
          Name:
            NameFull: Masalu N
      – PersonEntity:
          Name:
            NameFull: Kawira EL
      – PersonEntity:
          Name:
            NameFull: Kinyera T
      – PersonEntity:
          Name:
            NameFull: Otim I
      – PersonEntity:
          Name:
            NameFull: Nabalende H
      – PersonEntity:
          Name:
            NameFull: Dhudha H
      – PersonEntity:
          Name:
            NameFull: Candia B
      – PersonEntity:
          Name:
            NameFull: Abaru J
      – PersonEntity:
          Name:
            NameFull: Yan W
      – PersonEntity:
          Name:
            NameFull: Florez-Vargas O
      – PersonEntity:
          Name:
            NameFull: Xie Y
      – PersonEntity:
          Name:
            NameFull: Ho M
      – PersonEntity:
          Name:
            NameFull: Ayers LW
      – PersonEntity:
          Name:
            NameFull: Bhatia K
      – PersonEntity:
          Name:
            NameFull: Goedert JJ
      – PersonEntity:
          Name:
            NameFull: Pfeiffer RM
      – PersonEntity:
          Name:
            NameFull: Manning M
      – PersonEntity:
          Name:
            NameFull: Hutchinson A
      – PersonEntity:
          Name:
            NameFull: Cole N
      – PersonEntity:
          Name:
            NameFull: Luo W
      – PersonEntity:
          Name:
            NameFull: Hicks B
      – PersonEntity:
          Name:
            NameFull: Chagaluka G
      – PersonEntity:
          Name:
            NameFull: Johnston WT
      – PersonEntity:
          Name:
            NameFull: Mutalima N
      – PersonEntity:
          Name:
            NameFull: Borgstein E
      – PersonEntity:
          Name:
            NameFull: Liomba GN
      – PersonEntity:
          Name:
            NameFull: Kamiza S
      – PersonEntity:
          Name:
            NameFull: Mkandawire N
      – PersonEntity:
          Name:
            NameFull: Molyneux EM
      – PersonEntity:
          Name:
            NameFull: Mitambo C
      – PersonEntity:
          Name:
            NameFull: Newton R
      – PersonEntity:
          Name:
            NameFull: Siebert R
      – PersonEntity:
          Name:
            NameFull: Dean M
      – PersonEntity:
          Name:
            NameFull: Yeager M
      – PersonEntity:
          Name:
            NameFull: Chanock SJ
      – PersonEntity:
          Name:
            NameFull: Prokunina-Olsson L
      – PersonEntity:
          Name:
            NameFull: Mbulaiteye SM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2025 Sep
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5551
          Numbering:
            – Type: volume
              Value: 39
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Leukemia
              Type: main
ResultId 1