Efficacy and Safety of Biosimilar CT-P47 Versus Reference Tocilizumab: 1-Year Results of a Randomised, Active-Controlled, Double-Blind, Phase III Study in Patients with Rheumatoid Arthritis.

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Title: Efficacy and Safety of Biosimilar CT-P47 Versus Reference Tocilizumab: 1-Year Results of a Randomised, Active-Controlled, Double-Blind, Phase III Study in Patients with Rheumatoid Arthritis.
Authors: Burmester G; Charité - Universitätsmedizin Berlin, Berlin, Germany., Trefler J; REUMA RESEARCH, Warsaw, Poland., Racewicz A; Zdrowie Osteo-Medic, Białystok, Poland., Jaworski J; Klinika Reuma Park, Warsaw, Poland., Zielińska A; MICS Centrum Medyczne, Warsaw, Poland., Krogulec M; NZOZ Lecznica Mak-Med, Nadarzyn, Poland., Jeka S; MICS Centrum Medyczne Toruń, CM UMK, Toruń, Poland., Wojciechowski R; Clinic and Department of Rheumatology and Systemic Diseases of Connective Tissue, University Hospital No. 2, Bydgoszcz, Poland., Kolossa K; MICS Centrum Medyczne, Bydgoszcz, Poland., Dudek A; Centrum Medyczne Amed, Warsaw, Poland., Krajewska-Włodarczyk M; Clinic of Rheumatology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland., Hrycaj P; Department of Rheumatology, Municipal Hospital, Kościan, Poland., Klimiuk PA; Department of Rheumatology and Internal Diseases, Medical University of Bialystok and Inter Clinic Piotr Adrian Klimiuk, Białystok, Poland., Kim S; Celltrion, Inc., Incheon, Republic of Korea., Suh J; Celltrion, Inc., Incheon, Republic of Korea., Yang G; Celltrion, Inc., Incheon, Republic of Korea., Kim Y; Celltrion, Inc., Incheon, Republic of Korea., Jung Y; Celltrion, Inc., Incheon, Republic of Korea., Park G; Celltrion, Inc., Incheon, Republic of Korea., Smolen JS; Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. josef.smolen@meduniwien.ac.at.
Source: Clinical drug investigation [Clin Drug Investig] 2025 Aug; Vol. 45 (8), pp. 551-563. Date of Electronic Publication: 2025 Jul 12.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE
Database: MEDLINE Ultimate
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