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Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner.

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Title: Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner.
Authors: Bayar S; Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany., Seep L; Computational Life Sciences, Life & Medical Sciences (LIMES) Institute and Bonn Center for Mathematical Life Sciences, University of Bonn, 53115 Bonn, Germany., Doubková K; German Center for Neurodegenerative Diseases (DZNE), Dynamics of Neuronal Circuits Group, 53127 Bonn, Germany; Institute for Developmental Biology, RWTH Aachen University, Aachen 52074, Germany., Zurkovic J; Biochemistry & Cell Biology of Lipids, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany., Bülow MH; Neuronal Cell Metabolism, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany., Kierdorf K; Institute for Infection Prevention and Control, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Bauer R; Department of Molecular Developmental Biology, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany., Thiele C; Biochemistry & Cell Biology of Lipids, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany., Tavosanis G; German Center for Neurodegenerative Diseases (DZNE), Dynamics of Neuronal Circuits Group, 53127 Bonn, Germany; Institute for Developmental Biology, RWTH Aachen University, Aachen 52074, Germany., Hasenauer J; Computational Life Sciences, Life & Medical Sciences (LIMES) Institute and Bonn Center for Mathematical Life Sciences, University of Bonn, 53115 Bonn, Germany., Mass E; Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany. Electronic address: elvira.mass@uni-bonn.de.
Source: Cells & development [Cells Dev] 2025 Sep; Vol. 183, pp. 204040. Date of Electronic Publication: 2025 Jul 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101775611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2667-2901 (Electronic) Linking ISSN: 26672901 NLM ISO Abbreviation: Cells Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2667-2901
DOI:10.1016/j.cdev.2025.204040