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Functional humanization of 15-lipoxygenase-1 (Alox15) protects mice from dextran sodium sulfate induced intestinal inflammation.

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Title: Functional humanization of 15-lipoxygenase-1 (Alox15) protects mice from dextran sodium sulfate induced intestinal inflammation.
Authors: Reisch F; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany., Schäfer M; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany., Labuz D; Department of Experimental Anesthesiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany., Machelska H; Department of Experimental Anesthesiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany., Stehling S; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Püschel GP; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany. gpuesche@uni-potsdam.de., Rothe M; Lipidomix GmbH, Robert-Roessle-Str. 10, 1D-3125, Berlin, Germany., Heydeck D; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Kuhn H; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. hartmut.kuehn@charite.de.
Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2025 Jul 13; Vol. 30 (1), pp. 81. Date of Electronic Publication: 2025 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Functional humanization of 15-lipoxygenase-1 (Alox15) protects mice from dextran sodium sulfate induced intestinal inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Reisch+F%22">Reisch F</searchLink>; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Schäfer+M%22">Schäfer M</searchLink>; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Labuz+D%22">Labuz D</searchLink>; Department of Experimental Anesthesiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Machelska+H%22">Machelska H</searchLink>; Department of Experimental Anesthesiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Hindenburgdamm 30, D-12203, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Stehling+S%22">Stehling S</searchLink>; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Püschel+GP%22">Püschel GP</searchLink>; Institute for Nutritional Sciences, University Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany. gpuesche@uni-potsdam.de.<br /><searchLink fieldCode="AU" term="%22Rothe+M%22">Rothe M</searchLink>; Lipidomix GmbH, Robert-Roessle-Str. 10, 1D-3125, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Heydeck+D%22">Heydeck D</searchLink>; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kuhn+H%22">Kuhn H</searchLink>; Department of Biochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. hartmut.kuehn@charite.de.
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  Data: <searchLink fieldCode="JN" term="%229607427%22">Cellular & molecular biology letters</searchLink> [Cell Mol Biol Lett] 2025 Jul 13; Vol. 30 (1), pp. 81. <i>Date of Electronic Publication: </i>2025 Jul 13.
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              Text: 2025 Jul 13
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