History of chronic pain and opioid use is associated with cognitive decline and mild cognitive impairment.

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Title: History of chronic pain and opioid use is associated with cognitive decline and mild cognitive impairment.
Authors: Bell TR; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Elman JA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Gustavson DE; Institute for Behavioral Genetics and Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CA, USA., Lyons MJ; Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA., Fennema-Notestine C; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Williams ME; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Panizzon MS; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Pearce RC; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Reynolds CA; Institute for Behavioral Genetics and Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CA, USA., Sanderson-Cimino M; Memory and Aging Center, Weill Institute for Neurosciences, San Francisco, CA, USA., Toomey R; Department of Psychological and Brain Sciences, Boston University, Boston, MA, USA., Jak A; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA., Franz CE; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Kremen WS; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.; Center for Behavior Genetics of Aging, University of California, San Diego, La Jolla, CA, USA.
Source: Journal of the International Neuropsychological Society : JINS [J Int Neuropsychol Soc] 2025 May; Vol. 31 (4), pp. 307-317. Date of Electronic Publication: 2025 Jul 14.
Publication Type: Journal Article; Twin Study
Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 9503760 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7661 (Electronic) Linking ISSN: 13556177 NLM ISO Abbreviation: J Int Neuropsychol Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1469-7661
DOI:10.1017/S1355617725101057