A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms.
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| Title: | A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms. |
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| Authors: | Fu TM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Liu G; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Milkie DE; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Ruan X; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Görlitz F; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Shi Y; Lampe Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ferro V; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Divekar NS; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Wang W; Department of Chemistry, University of Illinois Chicago; Chicago, IL 60607, USA., York HM; Monash Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton/Melbourne, VIC, 3800, Australia., Kilic V; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Mueller M; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Liang Y; Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Daugird TA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gacha-Garay MJ; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA., Larkin KA; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA., Adikes RC; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA., Harrison N; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Shirazinejad C; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, USA., Williams S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Nourse JL; Department of Physiology and Biophysics, Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine 92697, USA., Sheu SH; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Gao L; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Li T; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States., Mondal C; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Achour K; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Hercule W; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Stabley D; Neuroimaging Laboratory, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA., Emmerich K; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Dong P; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Drubin D; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Liu ZJ; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Clapham D; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA., Mumm JS; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Koyama M; University of Toronto, Department of Cell and Systems Biology, Scarborough, Ontario, Canada., Killilea A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Bravo-Cordero JJ; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Keene CD; University of Washington BioRepository and Integrated Neuropathology (BRaIN) lab, Harborview Medical Center, Seattle, WA, USA., Luo L; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States., Kirchhausen T; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115., Pathak MM; Department of Physiology and Biophysics, Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine 92697, USA.; Department of Biomedical Engineering, and Center for Complex Systems Biology, University of California, Irvine, CA 92697 University of California, Irvine, Irvine 92697, USA., Arumugam S; Monash Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton/Melbourne, VIC, 3800, Australia.; European Molecular Laboratory Australia, Monash University, Clayton/ Melbourne, VIC 3800, Australia., Nunez JK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Gao R; Department of Chemistry, University of Illinois Chicago; Chicago, IL 60607, USA.; Department of Biological Sciences, University of Illinois Chicago, Chicago, IL 60607, USA., Matus DQ; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA., Martin BL; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA., Swinburne IA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA., Betzig E; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Department of Physics, Howard Hughes Medical Institute, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Legant WR; Lampe Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Upadhyayula S; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 03. Date of Electronic Publication: 2025 Jun 03. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40661351 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Fu+TM%22">Fu TM</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Milkie+DE%22">Milkie DE</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Ruan+X%22">Ruan X</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Görlitz+F%22">Görlitz F</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Lampe Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ferro+V%22">Ferro V</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Divekar+NS%22">Divekar NS</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Chemistry, University of Illinois Chicago; Chicago, IL 60607, USA.<br /><searchLink fieldCode="AU" term="%22York+HM%22">York HM</searchLink>; Monash Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton/Melbourne, VIC, 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Kilic+V%22">Kilic V</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Mueller+M%22">Mueller M</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.<br /><searchLink fieldCode="AU" term="%22Daugird+TA%22">Daugird TA</searchLink>; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gacha-Garay+MJ%22">Gacha-Garay MJ</searchLink>; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA.<br /><searchLink fieldCode="AU" term="%22Larkin+KA%22">Larkin KA</searchLink>; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA.<br /><searchLink fieldCode="AU" term="%22Adikes+RC%22">Adikes RC</searchLink>; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA.<br /><searchLink fieldCode="AU" term="%22Harrison+N%22">Harrison N</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Shirazinejad+C%22">Shirazinejad C</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+S%22">Williams S</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Nourse+JL%22">Nourse JL</searchLink>; Department of Physiology and Biophysics, Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine 92697, USA.<br /><searchLink fieldCode="AU" term="%22Sheu+SH%22">Sheu SH</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Mondal+C%22">Mondal C</searchLink>; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Achour+K%22">Achour K</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Hercule+W%22">Hercule W</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Stabley+D%22">Stabley D</searchLink>; Neuroimaging Laboratory, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.<br /><searchLink fieldCode="AU" term="%22Emmerich+K%22">Emmerich K</searchLink>; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Dong+P%22">Dong P</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Drubin+D%22">Drubin D</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Liu+ZJ%22">Liu ZJ</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Clapham+D%22">Clapham D</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.<br /><searchLink fieldCode="AU" term="%22Mumm+JS%22">Mumm JS</searchLink>; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Koyama+M%22">Koyama M</searchLink>; University of Toronto, Department of Cell and Systems Biology, Scarborough, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Killilea+A%22">Killilea A</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Bravo-Cordero+JJ%22">Bravo-Cordero JJ</searchLink>; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Keene+CD%22">Keene CD</searchLink>; University of Washington BioRepository and Integrated Neuropathology (BRaIN) lab, Harborview Medical Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Luo+L%22">Luo L</searchLink>; Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.<br /><searchLink fieldCode="AU" term="%22Kirchhausen+T%22">Kirchhausen T</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.; Department of Pediatrics, Harvard Medical School, Boston, MA 02115.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Pathak+MM%22">Pathak MM</searchLink>; Department of Physiology and Biophysics, Sue and Bill Gross Stem Cell Research Center, University of California Irvine, Irvine 92697, USA.; Department of Biomedical Engineering, and Center for Complex Systems Biology, University of California, Irvine, CA 92697 University of California, Irvine, Irvine 92697, USA.<br /><searchLink fieldCode="AU" term="%22Arumugam+S%22">Arumugam S</searchLink>; Monash Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton/Melbourne, VIC, 3800, Australia.; European Molecular Laboratory Australia, Monash University, Clayton/ Melbourne, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Nunez+JK%22">Nunez JK</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Gao+R%22">Gao R</searchLink>; Department of Chemistry, University of Illinois Chicago; Chicago, IL 60607, USA.; Department of Biological Sciences, University of Illinois Chicago, Chicago, IL 60607, USA.<br /><searchLink fieldCode="AU" term="%22Matus+DQ%22">Matus DQ</searchLink>; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA.<br /><searchLink fieldCode="AU" term="%22Martin+BL%22">Martin BL</searchLink>; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, USA.<br /><searchLink fieldCode="AU" term="%22Swinburne+IA%22">Swinburne IA</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Betzig+E%22">Betzig E</searchLink>; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; Department of Physics, Howard Hughes Medical Institute, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Legant+WR%22">Legant WR</searchLink>; Lampe Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Upadhyayula+S%22">Upadhyayula S</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.; 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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1101/2025.06.02.657494 Languages: – Code: eng Text: English Titles: – TitleFull: A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fu TM – PersonEntity: Name: NameFull: Liu G – PersonEntity: Name: NameFull: Milkie DE – PersonEntity: Name: NameFull: Ruan X – PersonEntity: Name: NameFull: Görlitz F – PersonEntity: Name: NameFull: Shi Y – PersonEntity: Name: NameFull: Ferro V – PersonEntity: Name: NameFull: Divekar NS – PersonEntity: Name: NameFull: Wang W – PersonEntity: Name: NameFull: York HM – PersonEntity: Name: NameFull: Kilic V – PersonEntity: Name: NameFull: Mueller M – PersonEntity: Name: NameFull: Liang Y – PersonEntity: Name: NameFull: Daugird TA – PersonEntity: Name: NameFull: Gacha-Garay MJ – PersonEntity: Name: NameFull: Larkin KA – PersonEntity: Name: NameFull: Adikes RC – PersonEntity: Name: NameFull: Harrison N – PersonEntity: Name: NameFull: Shirazinejad C – PersonEntity: Name: NameFull: Williams S – PersonEntity: Name: NameFull: Nourse JL – PersonEntity: Name: NameFull: Sheu SH – PersonEntity: Name: NameFull: Gao L – PersonEntity: Name: NameFull: Li T – PersonEntity: Name: NameFull: Mondal C – PersonEntity: Name: NameFull: Achour K – PersonEntity: Name: NameFull: Hercule W – PersonEntity: Name: NameFull: Stabley D – PersonEntity: Name: NameFull: Emmerich K – PersonEntity: Name: NameFull: Dong P – PersonEntity: Name: NameFull: Drubin D – PersonEntity: Name: NameFull: Liu ZJ – PersonEntity: Name: NameFull: Clapham D – PersonEntity: Name: NameFull: Mumm JS – PersonEntity: Name: NameFull: Koyama M – PersonEntity: Name: NameFull: Killilea A – PersonEntity: Name: NameFull: Bravo-Cordero JJ – PersonEntity: Name: NameFull: Keene CD – PersonEntity: Name: NameFull: Luo L – PersonEntity: Name: NameFull: Kirchhausen T – PersonEntity: Name: NameFull: Pathak MM – PersonEntity: Name: NameFull: Arumugam S – PersonEntity: Name: NameFull: Nunez JK – PersonEntity: Name: NameFull: Gao R – PersonEntity: Name: NameFull: Matus DQ – PersonEntity: Name: NameFull: Martin BL – PersonEntity: Name: NameFull: Swinburne IA – PersonEntity: Name: NameFull: Betzig E – PersonEntity: Name: NameFull: Legant WR – PersonEntity: Name: NameFull: Upadhyayula S IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 06 Text: 2025 Jun 03 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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