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Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma.

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Title: Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma.
Authors: Daly C; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK., Wright A; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK., Heukers R; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands., McKee CM; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK., Coll RC; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK., Evergren E; Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7AE, Belfast, UK.; Department of Biomedicine, Aarhus University, 8000 Aarhus Centrum, Denmark., Smit MJ; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands., Thomsen ARB; Department of Molecular Pathobiology, NYU Pain Research Center, NYU College of Dentistry, 433 1 Avenue, NY 10010, New York, USA., Plouffe B; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 15. Date of Electronic Publication: 2025 Jun 15.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Daly+C%22">Daly C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Wright+A%22">Wright A</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Heukers+R%22">Heukers R</searchLink>; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22McKee+CM%22">McKee CM</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Coll+RC%22">Coll RC</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Evergren+E%22">Evergren E</searchLink>; Patrick G Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7AE, Belfast, UK.; Department of Biomedicine, Aarhus University, 8000 Aarhus Centrum, Denmark.<br /><searchLink fieldCode="AU" term="%22Smit+MJ%22">Smit MJ</searchLink>; Department of Chemistry and Pharmaceutical Sciences, Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Thomsen+ARB%22">Thomsen ARB</searchLink>; Department of Molecular Pathobiology, NYU Pain Research Center, NYU College of Dentistry, 433 1 Avenue, NY 10010, New York, USA.<br /><searchLink fieldCode="AU" term="%22Plouffe+B%22">Plouffe B</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Rd, BT9 7BL, Belfast, UK.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Jun 15. <i>Date of Electronic Publication: </i>2025 Jun 15.
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        Value: 10.1101/2025.06.12.659276
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              Text: 2025 Jun 15
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