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Opposing effects of systemic and pancreas-specific inhibition of BCKDK on pancreatic carcinogenesis.

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Title: Opposing effects of systemic and pancreas-specific inhibition of BCKDK on pancreatic carcinogenesis.
Authors: Noji MC; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA., Demetriadou C; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Landis M; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Pennise J; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Pinheiro LV; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Jaccard A; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Chatoff A; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Drummond J; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Guo K; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Azor R; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Robertson MR; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Kawakami R; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA., Marcinkiewicz MM; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Tobias JW; Penn Genomics and Sequencing Core, University of Pennsylvania, Philadelphia, PA., Snyder NW; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA., Feldser D; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA., Arany Z; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA., Wellen KE; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 15. Date of Electronic Publication: 2025 Jun 15.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Noji+MC%22">Noji MC</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Demetriadou+C%22">Demetriadou C</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Landis+M%22">Landis M</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pennise+J%22">Pennise J</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pinheiro+LV%22">Pinheiro LV</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Jaccard+A%22">Jaccard A</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Chatoff+A%22">Chatoff A</searchLink>; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Drummond+J%22">Drummond J</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Guo+K%22">Guo K</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Azor+R%22">Azor R</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Robertson+MR%22">Robertson MR</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Kawakami+R%22">Kawakami R</searchLink>; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Marcinkiewicz+MM%22">Marcinkiewicz MM</searchLink>; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Tobias+JW%22">Tobias JW</searchLink>; Penn Genomics and Sequencing Core, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Snyder+NW%22">Snyder NW</searchLink>; Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Feldser+D%22">Feldser D</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Arany+Z%22">Arany Z</searchLink>; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Wellen+KE%22">Wellen KE</searchLink>; Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA.
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              Text: 2025 Jun 15
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