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A combined in vitro, in vivo and in silico approach for the discovery of bioactive molecules from Corchorus olitorius L as pancreatic lipase inhibitors, interleukin-6 and tumor necrosis factor alpha TNF-α.

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Title: A combined in vitro, in vivo and in silico approach for the discovery of bioactive molecules from Corchorus olitorius L as pancreatic lipase inhibitors, interleukin-6 and tumor necrosis factor alpha TNF-α.
Authors: Djeziri FZ; Laboratory of Natural Product (LAPRONA), Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria., Ghalem M; Laboratory of Natural Product (LAPRONA), Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria. ghalemmeriem@yahoo.fr.; Laboratory of Natural and Bio-Actives SubstancesDepartment of ChemistryFaculty of Science, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria. ghalemmeriem@yahoo.fr., Mesli F; Laboratory of Natural and Bio-Actives SubstancesDepartment of ChemistryFaculty of Science, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria. meslifouzia2018@gmail.com., Benzazoua N; Laboratory of Histology, Embryology and Clinical Genetics, Department of Medicine, Faculty of Medicine, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria.; Hospital Center (CHU Tlemcen), Boudghene Polyclinic, Tlemcen, Algeria., Yelles N; Laboratory Toxicomed, Hospital Center (CHU Tlemcen), Department of Medicine, Faculty of Medicine, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria., Ghalem S; Laboratory of Natural and Bio-Actives SubstancesDepartment of ChemistryFaculty of Science, University Abou-Bekr Belkaïd, 13000, Tlemcen, Algeria.
Source: Journal of molecular histology [J Mol Histol] 2025 Jul 15; Vol. 56 (4), pp. 229. Date of Electronic Publication: 2025 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 101193653 Publication Model: Electronic Cited Medium: Internet ISSN: 1567-2387 (Electronic) Linking ISSN: 15672379 NLM ISO Abbreviation: J Mol Histol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1567-2387
DOI:10.1007/s10735-025-10514-3