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Comprehensive in vitro assessment of drug-drug interactions of the major human metabolite of soticlestat.

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Title: Comprehensive in vitro assessment of drug-drug interactions of the major human metabolite of soticlestat.
Authors: Ugajin M; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Nishihara M; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Ballard TE; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA., Cohen L; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA., Chuang BC; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA., Takahashi J; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan., Hirabayashi H; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.
Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2025 Jun; Vol. 55 (6), pp. 499-506. Date of Electronic Publication: 2025 Jul 27.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comprehensive in vitro assessment of drug-drug interactions of the major human metabolite of soticlestat.
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  Data: <searchLink fieldCode="AU" term="%22Ugajin+M%22">Ugajin M</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Nishihara+M%22">Nishihara M</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ballard+TE%22">Ballard TE</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+L%22">Cohen L</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chuang+BC%22">Chuang BC</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Development Center Americas, Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Takahashi+J%22">Takahashi J</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hirabayashi+H%22">Hirabayashi H</searchLink>; Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa, Japan.
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  Data: <searchLink fieldCode="JN" term="%221306665%22">Xenobiotica; the fate of foreign compounds in biological systems</searchLink> [Xenobiotica] 2025 Jun; Vol. 55 (6), pp. 499-506. <i>Date of Electronic Publication: </i>2025 Jul 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>1306665 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1366-5928 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200498254%22">00498254 </searchLink><i>NLM ISO Abbreviation: </i>Xenobiotica <i>Subsets: </i>MEDLINE
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        Value: 10.1080/00498254.2025.2532649
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        Text: English
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      – TitleFull: Comprehensive in vitro assessment of drug-drug interactions of the major human metabolite of soticlestat.
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              Text: 2025 Jun
              Type: published
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