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Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081.

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Title: Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081.
Authors: Durm G; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA gdurm@iu.edu., Mamdani H; Department of Oncology, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA., Althouse S; Indiana University Richard M Fairbanks Department of Biostatistics, Indianapolis, Indiana, USA., Perkins S; Indiana University Richard M Fairbanks Department of Biostatistics, Indianapolis, Indiana, USA., Jabbour SK; Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA., Ganti AK; Oncology-Hematology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; VA Nebraska-Western Iowa Health Care System, Grand Island, Nebraska, USA., Jalal S; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Richard L Roudebush VA Medical Center, Indianapolis, Indiana, USA., Chesney J; University of Louisville School of Medicine, Louisville, Kentucky, USA., Naidoo J; Beaumont Hospital, Dublin, Ireland.; RCSI University of Health Sciences, Dublin, Ireland.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA., Hrinczenko B; Michigan State University College of Human Medicine, East Lansing, Michigan, USA., Fidler MJ; Rush University Medical Center, Chicago, Illinois, USA., Leal TA; Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, USA., Feldman L; University of Illinois Cancer Center, Chicago, Illinois, USA.; Jesse Brown VA Medical Center, Chicago, Illinois, USA., Fujioka N; University of Minnesota, Minneapolis, Minnesota, USA., Hanna NH; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Jul 15; Vol. 13 (7). Date of Electronic Publication: 2025 Jul 15.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081.
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  Data: <searchLink fieldCode="AU" term="%22Durm+G%22">Durm G</searchLink>; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA gdurm@iu.edu.<br /><searchLink fieldCode="AU" term="%22Mamdani+H%22">Mamdani H</searchLink>; Department of Oncology, Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Althouse+S%22">Althouse S</searchLink>; Indiana University Richard M Fairbanks Department of Biostatistics, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Perkins+S%22">Perkins S</searchLink>; Indiana University Richard M Fairbanks Department of Biostatistics, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Jabbour+SK%22">Jabbour SK</searchLink>; Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ganti+AK%22">Ganti AK</searchLink>; Oncology-Hematology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; VA Nebraska-Western Iowa Health Care System, Grand Island, Nebraska, USA.<br /><searchLink fieldCode="AU" term="%22Jalal+S%22">Jalal S</searchLink>; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.; Richard L Roudebush VA Medical Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Chesney+J%22">Chesney J</searchLink>; University of Louisville School of Medicine, Louisville, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Naidoo+J%22">Naidoo J</searchLink>; Beaumont Hospital, Dublin, Ireland.; RCSI University of Health Sciences, Dublin, Ireland.; Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hrinczenko+B%22">Hrinczenko B</searchLink>; Michigan State University College of Human Medicine, East Lansing, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Fidler+MJ%22">Fidler MJ</searchLink>; Rush University Medical Center, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Leal+TA%22">Leal TA</searchLink>; Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Feldman+L%22">Feldman L</searchLink>; University of Illinois Cancer Center, Chicago, Illinois, USA.; Jesse Brown VA Medical Center, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Fujioka+N%22">Fujioka N</searchLink>; University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Hanna+NH%22">Hanna NH</searchLink>; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana, USA.
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  Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2025 Jul 15; Vol. 13 (7). <i>Date of Electronic Publication: </i>2025 Jul 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jitc-2024-010316
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      – TitleFull: Randomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081.
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              Text: 2025 Jul 15
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