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Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism.

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Title: Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism.
Authors: Grice GL; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Minogue E; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Coates HW; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Debela M; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Stopforth RJ; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Wit N; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Li Z; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Crowley JP; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Kaser A; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Kaneider-Kaser N; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK., Antrobus PR; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK., Haigis MC; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Johnson RS; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden. randall.johnson@ki.se., Nathan JA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, UK. jan33@cam.ac.uk.
Source: Nature chemical biology [Nat Chem Biol] 2025 Dec; Vol. 21 (12), pp. 1915-1926. Date of Electronic Publication: 2025 Jul 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
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