The METTL3/IGF2BP1 axis-mediated m6 A modification of TRIM11 mRNA suppresses ferroptosis and accelerates malignant progression in non-small cell lung cancer cells by degrading ACSL4.

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Title: The METTL3/IGF2BP1 axis-mediated m6 A modification of TRIM11 mRNA suppresses ferroptosis and accelerates malignant progression in non-small cell lung cancer cells by degrading ACSL4.
Authors: Chen H; Department of Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.; Department of Oncology, Cangzhou People's Hospital, Cangzhou, China., Wang C; Department of Oncology, Cangzhou People's Hospital, Cangzhou, China., Dai H; Department of Oncology, Cangzhou People's Hospital, Cangzhou, China., Shi J; Department of Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China. 46900195@hebmu.edu.cn.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jan; Vol. 399 (1), pp. 665-681. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1912
DOI:10.1007/s00210-025-04207-7