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Development of Heteroaromatic Silicon Fluoride Acceptors (HetSiFAs) for 18F-Labeled Radiopharmaceuticals.

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Title: Development of Heteroaromatic Silicon Fluoride Acceptors (HetSiFAs) for 18F-Labeled Radiopharmaceuticals.
Authors: Singleton TA; Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec H3A 2B4, Canada.; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States., Jun H; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada., Deore PS; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., Estrada C; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., Atienza BJP; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., Delecueillerie J; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., El-Zaria ME; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., Genady AR; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., Zhao E; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada., Edelmann S; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada., Burley D; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada., Silva LR; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., Marfatia YM; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., Ibrahim AA; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., DeRoy PL; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., Larivée A; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada., Toutov AA; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States., Waldmann CM; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States., Sadeghi S; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada., Lumb JP; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada., Kostikov A; Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec H3A 2B4, Canada.; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.
Source: Journal of medicinal chemistry [J Med Chem] 2025 Aug 14; Vol. 68 (15), pp. 16114-16137. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of Heteroaromatic Silicon Fluoride Acceptors (HetSiFAs) for <superscript>18</superscript>F-Labeled Radiopharmaceuticals.
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  Data: <searchLink fieldCode="AU" term="%22Singleton+TA%22">Singleton TA</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec H3A 2B4, Canada.; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States.<br /><searchLink fieldCode="AU" term="%22Jun+H%22">Jun H</searchLink>; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.<br /><searchLink fieldCode="AU" term="%22Deore+PS%22">Deore PS</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Estrada+C%22">Estrada C</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Atienza+BJP%22">Atienza BJP</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Delecueillerie+J%22">Delecueillerie J</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22El-Zaria+ME%22">El-Zaria ME</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22Genady+AR%22">Genady AR</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22Zhao+E%22">Zhao E</searchLink>; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.<br /><searchLink fieldCode="AU" term="%22Edelmann+S%22">Edelmann S</searchLink>; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.<br /><searchLink fieldCode="AU" term="%22Burley+D%22">Burley D</searchLink>; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.<br /><searchLink fieldCode="AU" term="%22Silva+LR%22">Silva LR</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22Marfatia+YM%22">Marfatia YM</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22Ibrahim+AA%22">Ibrahim AA</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22DeRoy+PL%22">DeRoy PL</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Larivée+A%22">Larivée A</searchLink>; Paraza Pharma Inc., Montréal, Quebec H4S 2E1, Canada.<br /><searchLink fieldCode="AU" term="%22Toutov+AA%22">Toutov AA</searchLink>; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States.<br /><searchLink fieldCode="AU" term="%22Waldmann+CM%22">Waldmann CM</searchLink>; Fuzionaire Theranostics, Inc., The Woodlands, Texas 77380, United States.<br /><searchLink fieldCode="AU" term="%22Sadeghi+S%22">Sadeghi S</searchLink>; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario L8S 4M1, Canada.<br /><searchLink fieldCode="AU" term="%22Lumb+JP%22">Lumb JP</searchLink>; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.<br /><searchLink fieldCode="AU" term="%22Kostikov+A%22">Kostikov A</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montréal, Quebec H3A 2B4, Canada.; Department of Chemistry, McGill University, Montréal, Quebec H3A 0B8, Canada.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2025 Aug 14; Vol. 68 (15), pp. 16114-16137. <i>Date of Electronic Publication: </i>2025 Jul 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.jmedchem.5c01087
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        Text: English
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              Text: 2025 Aug 14
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