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Use of Disease-Modifying Therapies in Patients With Late-Onset Multiple Sclerosis.

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Title: Use of Disease-Modifying Therapies in Patients With Late-Onset Multiple Sclerosis.
Authors: Robin C; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France., Rollot F; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France., Lefort M; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France., Casey R; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France., Vukusic S; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France., Mathey G; Department of Neurology, Nancy University Hospital, F-54035 Nancy, Université de Lorraine, Inserm, INSPIIRE, France., Ciron J; CHU de Toulouse, CRC-SEP, Department of Neurology, Toulouse Cedex 9, INSERM UMR1291 - CNRS UMR5051, Université Toulouse III, Infinity, Toulouse Cedex 3, France., De Seze J; CHU de Strasbourg, Department of Neurology and Clinical Investigation Center, CIC 1434, INSERM 1434, France., Stankoff B; Département de neurologie, Hôpital Pitié-Salpêtrière, APHP, Paris, Centre de Ressources et de Compétences SEP Paris, France.; Sorbonne Universités, Paris Brain Institute, ICM, Inserm UMR S 1127, CNRS UMR 7225, and Department of Neurology, AP-HP, Hôpital de la Pitié Salpêtrière F-75013 Paris, France., Maillart E; Département de neurologie, Hôpital Pitié-Salpêtrière, APHP, Paris, Centre de Ressources et de Compétences SEP Paris, France., Ruet A; Department of Neurology, University Hospital of Bordeaux, France Neurocentre Magendie, Bordeaux University, INSERM U1215, France., Labauge PM; CHU de Montpellier, MS Unit, F-34295 Montpellier Cedex 5, University of Montpellier (MUSE), France., Kwiatkowski A; Department of Neurology, Hôpital Saint Vincent de Paul, Groupement des Hôpitaux de l'Institut Catholique de Lille, France., Zephir H; CHU Lille, CRCSEP Lille, Univ Lille, U1172, France., Papeix C; Department of Neurology, Foundation Adolphe de Rothschild Hospital, Université Paris Cité, France., Defer G; Department of Neurology, CHU de Caen, MS expert centre, avenue de la Côte-de-Nacre, Normandy University, Caen, France., Lebrun-Frenay C; Neurology, UR2CA_URRIS, Centre Hospitalier Universitaire Pasteur2, Université Nice Côte d'Azur, Nice, France., Moreau T; Department of Neurology, CHU de Dijon, EA4184, France., Laplaud DA; CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, UMR 1064, CIC INSERM 1413, CRC-SEP Pays de la Loire, Service de Neurologie, Nantes Université, France., Berger E; CHU de Besançon, Service de Neurologie 25 030, France., Clavelou P; Department of Neurology, and INSERM NeuroDol U1107, CHU Clermont-Ferrand, CRC SEP Auvergne., Thouvenot E; CHU Nimes, Service de Neurologie, Institut de Génomique Fonctionnelle, Univ Montpellier, CNRS, INSERM, France., Heinzlef O; Departement of Neurology, Centre de ressource et compétences SEP IDF Ouest, Hôpital de Poissy, France., Pelletier J; APHM, Hôpital de la Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, Aix Marseille Univ, France., Casez O; Department of Neurology, CHU Grenoble Alpes, Neurology MS Clinic Grenoble, Grenoble Alpes university hospital, La Tronche., Bourre B; Departement of Neurology, CHU de Rouen, France., Wahab A; Department of Neurology, APHP, Hôpital Henri Mondor, Créteil, France., Magy L; Department of Neurology, CHU de Limoges, Hôpital Dupuytren, France., Moulin S; Department of Neurology, CHU de Reims, CRC-SEP, Reims cedex, France., Camdessanche JP; Department of Neurology, CHU de Saint-Étienne, Hôpital Nord, France., Doghri I; CHU de Tours, Hôpital Bretonneau, CRC SEP and Department of Neurology, France., Sarov M; Department of Neurology, CHU Bicêtre, Le Kremlin Bicêtre, France., Hankiewicz K; Department of Neurology, Hôpital Pierre Delafontaine, Centre Hospitalier de Saint-Denis, France., Pottier C; Depatrment of Neurology, Hôpital Novo, Site Pontoise, France., Dos Santos A; Department of Neurology, CHU La Milétrie, Hôpital Jean Bernard, CIC INSERM 1402, Poitiers, France., Manchon E; Department of Neurology, CH de Gonesse, France., Tchikviladze M; Department of Neurology, Hôpital Foch, Suresnes, France; and., Nifle C; Department of Neurology, Centre hospitalier de Versailles, Le Chesnay, France., Kerbrat A; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France., Edan G; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France., Le Page E; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France., Michel L; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France.
Corporate Authors: as the OFSEP Investigators
Source: Neurology [Neurology] 2025 Aug 12; Vol. 105 (3), pp. e213744. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: Use of Disease-Modifying Therapies in Patients With Late-Onset Multiple Sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Robin+C%22">Robin C</searchLink>; Neurology Department, Rennes University Hospital, France.; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France.<br /><searchLink fieldCode="AU" term="%22Rollot+F%22">Rollot F</searchLink>; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France.<br /><searchLink fieldCode="AU" term="%22Lefort+M%22">Lefort M</searchLink>; Clinical Neuroscience Centre, CIC_P1414 INSERM, University Hospital, Rennes University, France.<br /><searchLink fieldCode="AU" term="%22Casey+R%22">Casey R</searchLink>; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France.<br /><searchLink fieldCode="AU" term="%22Vukusic+S%22">Vukusic S</searchLink>; Université de Lyon, Université Claude Bernard Lyon 1, France.; Hospices Civils de Lyon, Service de Neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation, Bron, France.; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France.; Eugène Devic EDMUS Foundation Against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France.<br /><searchLink fieldCode="AU" term="%22Mathey+G%22">Mathey G</searchLink>; Department of Neurology, Nancy University Hospital, F-54035 Nancy, Université de Lorraine, Inserm, INSPIIRE, France.<br /><searchLink fieldCode="AU" term="%22Ciron+J%22">Ciron J</searchLink>; CHU de Toulouse, CRC-SEP, Department of Neurology, Toulouse Cedex 9, INSERM UMR1291 - CNRS UMR5051, Université Toulouse III, Infinity, Toulouse Cedex 3, France.<br /><searchLink fieldCode="AU" term="%22De+Seze+J%22">De Seze J</searchLink>; CHU de Strasbourg, Department of Neurology and Clinical Investigation Center, CIC 1434, INSERM 1434, France.<br /><searchLink fieldCode="AU" term="%22Stankoff+B%22">Stankoff B</searchLink>; Département de neurologie, Hôpital Pitié-Salpêtrière, APHP, Paris, Centre de Ressources et de Compétences SEP Paris, France.; Sorbonne Universités, Paris Brain Institute, ICM, Inserm UMR S 1127, CNRS UMR 7225, and Department of Neurology, AP-HP, Hôpital de la Pitié Salpêtrière F-75013 Paris, France.<br /><searchLink fieldCode="AU" term="%22Maillart+E%22">Maillart E</searchLink>; Département de neurologie, Hôpital Pitié-Salpêtrière, APHP, Paris, Centre de Ressources et de Compétences SEP Paris, France.<br /><searchLink fieldCode="AU" term="%22Ruet+A%22">Ruet A</searchLink>; Department of Neurology, University Hospital of Bordeaux, France Neurocentre Magendie, Bordeaux University, INSERM U1215, France.<br /><searchLink fieldCode="AU" term="%22Labauge+PM%22">Labauge PM</searchLink>; CHU de Montpellier, MS Unit, F-34295 Montpellier Cedex 5, University of Montpellier (MUSE), France.<br /><searchLink fieldCode="AU" term="%22Kwiatkowski+A%22">Kwiatkowski A</searchLink>; Department of Neurology, Hôpital Saint Vincent de Paul, Groupement des Hôpitaux de l'Institut Catholique de Lille, France.<br /><searchLink fieldCode="AU" term="%22Zephir+H%22">Zephir H</searchLink>; CHU Lille, CRCSEP Lille, Univ Lille, U1172, France.<br /><searchLink fieldCode="AU" term="%22Papeix+C%22">Papeix C</searchLink>; Department of Neurology, Foundation Adolphe de Rothschild Hospital, Université Paris Cité, France.<br /><searchLink fieldCode="AU" term="%22Defer+G%22">Defer G</searchLink>; Department of Neurology, CHU de Caen, MS expert centre, avenue de la Côte-de-Nacre, Normandy University, Caen, France.<br /><searchLink fieldCode="AU" term="%22Lebrun-Frenay+C%22">Lebrun-Frenay C</searchLink>; Neurology, UR2CA_URRIS, Centre Hospitalier Universitaire Pasteur2, Université Nice Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Moreau+T%22">Moreau T</searchLink>; Department of Neurology, CHU de Dijon, EA4184, France.<br /><searchLink fieldCode="AU" term="%22Laplaud+DA%22">Laplaud DA</searchLink>; CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, UMR 1064, CIC INSERM 1413, CRC-SEP Pays de la Loire, Service de Neurologie, Nantes Université, France.<br /><searchLink fieldCode="AU" term="%22Berger+E%22">Berger E</searchLink>; CHU de Besançon, Service de Neurologie 25 030, France.<br /><searchLink fieldCode="AU" term="%22Clavelou+P%22">Clavelou P</searchLink>; Department of Neurology, and INSERM NeuroDol U1107, CHU Clermont-Ferrand, CRC SEP Auvergne.<br /><searchLink fieldCode="AU" term="%22Thouvenot+E%22">Thouvenot E</searchLink>; CHU Nimes, Service de Neurologie, Institut de Génomique Fonctionnelle, Univ Montpellier, CNRS, INSERM, France.<br /><searchLink fieldCode="AU" term="%22Heinzlef+O%22">Heinzlef O</searchLink>; 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